CLINICAL TRIAL: BRAIN FITNESS IN OLDER ADULTS (B-FIT)

临床试验：老年人的大脑健康 (B-FIT)

• 批准号: 7951384
• 负责人: Paul Laurienti
• 金额: $ 0.34万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2010-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951384
• 关键词: Adult; Age; Age-Years; Aging; Attention; Behavioral; Brain; Clinical Research; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Conflict (Psychology); Elderly; Exhibits; Funding; Grant; Individual; Institution; Modality; Pattern; Performance; Population; Quality of life; Research; Research Personnel; Resources; Sensory; Source; Stimulus; Training Programs; United States; United States National Institutes of Health; aged; disability; distraction; fitness; multisensory; relating to nervous system; response; sensory system; vigilance

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Adults over 65 years of age have become the most rapidly growing sector of the United States population. It is of considerable concern that all sensory systems exhibit diminished function with age. Many of the disabilities associated with aging that may impact the quality of life may be impacted by changes in the integration of information from multiple sensory modalities. Distractions from unattended or background stimuli in multisensory stimulation paradigms are consistently increased in aged individuals, and the corresponding neural responses to such stimuli are also abnormally increased. The behavioral disruptions caused by task-irrelevant stimuli are accompanied by alterations in patterns of brain activity in older adults during tasks that require the suppression of interfering or conflicting information. In addition, while older adults maintain vigilance and sustained attention abilities equivalent to those of young subjects, their performance on selective or divided attention tasks deteriorates significantly. The study proposed here will determine the extent and magnitude of functional changes in brain activity in older adults who participate in an attention training program.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 65岁以上的成年人已成为美国人口中增长最快的部分。 随着年龄的增长，所有的感觉系统都表现出功能减退，这是相当令人担忧的。许多与衰老相关的可能影响生活质量的残疾可能会受到来自多种感觉方式的信息整合变化的影响。 在多感觉刺激范例中，来自无人看管或背景刺激的分心在老年个体中持续增加，并且对这种刺激的相应神经反应也异常增加。由任务无关的刺激引起的行为中断伴随着老年人在需要抑制干扰或冲突信息的任务期间大脑活动模式的改变。此外，虽然老年人保持警惕和持续的注意力能力相当于年轻人，但他们在选择性或分散注意力任务上的表现显着恶化。 这项研究将确定参与注意力训练计划的老年人大脑活动功能变化的程度和幅度。