MEMBRANE VOLTAGE IN SPINAL CORD/MUSCLE REGENERATION

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 该项目涉及膜电压在脊髓/肌肉再生中的作用。我们已经发现，在伤口中产生的H+流量是必要的，足以驱动完整的尾巴再生的蝌蚪。 我们目前的工作重点是将其扩展到生物医学应用中，以增强再生。这项工作目前正在编写出版。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project involves the role of membrane voltage in spinal cord/muscle regeneration. We have discovered that a H+ flux produced in the wound is necessary and sufficient to drive complete tail regeneration in tadpoles. Our current work focuses on extending this into a biomedical application for augmentation of regeneration. This work is currently being written up for publication.