Determining the stability and conidial yield of the entomogenous fungus Metarhizium anisopliae

测定虫生真菌绿僵菌的稳定性和分生孢子产量

• 批准号: NE/E522308/1
• 负责人: Tariq Butt
• 金额: $ 10.31万
• 依托单位: Swansea University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=NE%2FE522308%2F1
• 关键词: Determining; stability; conidial; yield; entomogenous

Three strains of the insect-pathogenic fungus Metarhizium anisopliae have been identified through an earlier NERC funded project that are highly pathogenic to ticks, which are important pests of livestock and vectors of zoonotic diseases. Subsequent studies showed that these strains are also efficacious against insect pests. Two independent consultants have established that markets exist for Metarhizium-based products but these must be produced economically and without a decline in quality in order to compete with conventional chemical pesticides. Two key factors that greatly influence the product cost are the stability of the strains and conidial yield. Fungi can readily degenerate (lose virulence and exhibit phenotypic instability) when continuously maintained on nutrient rich media. The focus of this project is to determine the stability and conidial yield of the Metarhizium strains and establish which are worth commercialising.

通过早期NERC资助的项目，已经鉴定出三种对蜱具有高致病性的昆虫病原性真菌金龟子绿僵菌菌株，蜱是牲畜的重要害虫和人畜共患疾病的媒介。随后的研究表明，这些菌株对昆虫害虫也有效。两名独立的顾问已经确定，绿僵菌产品存在市场，但这些产品必须以经济的方式生产，并且质量不下降，以便与传统的化学农药竞争。菌株的稳定性和产孢量是影响生产成本的两个关键因素。真菌在营养丰富的培养基上持续生长时，很容易退化（丧失毒力并表现出表型不稳定性）。本项目的重点是确定绿僵菌菌株的稳定性和产孢量，并确定哪些菌株值得商业化。