ASSESSMENT OF REPRODUCIBILITY OF 3HE MRI OXYGEN MEASUREMENTS
ASSESSMENT OF REPRODUCIBILITY OF 3HE MRI OXYGEN MEASUREMENTS
批准号:
7955346
负责人:
JINGHUA YU
金额:
$0.56万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-06-01 至 2010-05-31
关键词:
AnimalsComputer Retrieval of Information on Scientific Projects DatabaseDependenceFamily suidaeFundingGrantInstitutionLiteratureLungMagnetic ResonanceMagnetic Resonance ImagingMapsMeasurementModelingNoiseOxygenPartial PressureReportingReproducibilityResearchResearch PersonnelResolutionResourcesScanningSourceTechniquesTimeUncertaintyUnited States National Institutes of HealthWorkbasehuman subjectoptical imaging
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
肺氧分压(pO 2)和氧耗率(ODR)是两个重要的
肺功能参数。超极化(HP)~ 3 He T_1对局部氧的依赖性
浓度为pO 2区域分布的高分辨率绘图提供了基础
和ODR虽然氧敏HP ~ 3 He MRI技术已应用于
人类受试者和几种动物物种,重现性研究很少报告,
文学本工作提出了一个初步的重复性研究的猪模型。在本研究中,
诸如测量定时和翻转角等重要扫描参数被优化,
最小化噪声引起的测量不确定性。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Pulmonary partial pressure of oxygen (pO2) and oxygen depletion rate (ODR) are two important
functional parameters of lung. The dependence of hyperpolarized (HP) 3He T1 on local oxygen
concentration provides the basis for high-resolution mapping of the regional distributions of pO2
and ODR in the lung. Although the oxygen-sensitive HP 3He MRI technique has been applied in
human subjects and several animal species, reproducibility studies are rarely reported in the
literature. This work presents a preliminary reproducibility study on a pig model. In this study,
important scan parameters, such as measurement timing and flip angle, are optimized to
minimize the noise-induced measurement uncertainty.
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会议论文
SIMULTANEOUS MEASUREMENTS OF ADC AND PO2
-
批准号:7955305
-
项目类别:
-
资助金额:$1.67万
-
财政年份:2009
-
负责人:JINGHUA YU
-
依托单位:
SIMULTANEOUS MEASUREMENTS OF ADC AND PO2
-
批准号:7723802
-
项目类别:
-
资助金额:$1.63万
-
财政年份:2008
-
负责人:JINGHUA YU
-
依托单位:
SIMULTANEOUS MEASUREMENTS USING HYPERPOLARIZED 3HE MRI
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批准号:7600807
-
项目类别:
-
资助金额:$3.3万
-
财政年份:2007
-
负责人:JINGHUA YU
-
依托单位:
FLIP ANGLE CALIBRATION FOR HIGH RESOLUTION MAPPING
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批准号:7600811
-
项目类别:
-
资助金额:$5.5万
-
财政年份:2007
-
负责人:JINGHUA YU
-
依托单位:
SIMULTANEOUS MEASUREMENTS USING HYPERPOLARIZED 3HE MRI
-
批准号:7357859
-
项目类别:
-
资助金额:$2.91万
-
财政年份:2006
-
负责人:JINGHUA YU
-
依托单位:
QUANTITATIVE MEASURE OF REGIONAL VENTILATION & PERFUSION FROM STATIC MRI IMAGES
-
批准号:7357844
-
项目类别:
-
资助金额:$2.18万
-
财政年份:2006
-
负责人:JINGHUA YU
-
依托单位:
MEASUREMENTS OF REGIONAL ALVEOLAR OXYGEN PRESSURE BY HYPERPOLARIZED 3HE MRI
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批准号:7357866
-
项目类别:
-
资助金额:$13.03万
-
财政年份:2006
-
负责人:JINGHUA YU
-
依托单位: