课题基金 / 基金详情

HIGH-RESOLUTION REFINEMENT OF PROTEIN STRUCTURE FRO NMR CHEMICAL SHIFTS

HIGH-RESOLUTION REFINEMENT OF PROTEIN STRUCTURE FRO NMR CHEMICAL SHIFTS
利用 NMR 化学位移对蛋白质结构进行高分辨率精修
批准号：
7957350
负责人：
CHARLES L BROOKS
金额：
$5.94万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-09-01 至 2010-08-31
来源：
https://reporter.nih.gov/project-details/7957350
关键词：
AreaArenavirusChemicalsComputer Retrieval of Information on Scientific Projects DatabaseDataFundingGrantInstitutionInvestigationResearchResearch PersonnelResolutionResourcesSourceStructureUnited States National Institutes of HealthWorkbasemolecular dynamicsmulti-scale modelingplasma protein Zprotein structurestructural biologytool

项目摘要

项目成果

CHARLES L BROOKS的其他基金

相似基金

相关文献

中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在一个新的研究领域，我们正在扩展我们早期的工作，即将副本交换分子动力学与基于核磁共振数据的原子级结构的精细化相结合。在目前的努力中，我们仅利用化学位移数据作为对ArenaVirus Z-蛋白质结构集合的细化的限制。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In a new area of investigation, we are extending our earlier work that combined replica exchange molecular dynamics with the refinement of atomic level structures based on NMR data. In the current efforts, we have utilized chemical shift data alone as a constraint on the refinement of a structural ensemble of the arenavirus Z-protein.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Theory and Modeling of Biomolecules and their Interactions - Equipment Supplement
Theory and Modeling of Biomolecules and their Interactions
Theory and Modeling of Biomolecules and their Interactions - Equipment Supplement
Theory and Modeling of Biomolecules and their Interactions
海外基金