METAL SPECIATION IN THE YEAST S CEREVISIAE AS A FUNCTION OF RESPIRATORY OSCILLA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这个项目的总体目标是描述在细胞周期中发生的酵母金属动态平衡的变化。整个项目包括金属成像研究(将在APS进行)和元素分析(将在密歇根进行)。本提案要求使用高通量XAS，利用束流时间来确定金属氧化状态和形态随细胞周期的变化情况。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goal of this project is to characterize the variations in yeast metal homeostasis that take place during the cell cycle. Included within the overall project are metal imaging studies (to be performed at the APS) and elemental analysis(to be performed at Michigan). The present proposal requests beam time to be used to determine how metal oxidation state and speciation varies as a function of cell cycle using high-throughput XAS.