BIOMED WORKSHOP: JUNE 25-29, 2007 COMPUTATIONAL METHODS FOR SPATIALLY REALISTI

BIOMED 研讨会：2007 年 6 月 25-29 日 空间现实的计算方法

• 批准号: 7956288
• 负责人: JOEL R. STILES
• 金额: $ 0.08万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956288
• 关键词: 3-Dimensional; Biochemical; Biological; Biomedical Research; Computer Retrieval of Information on Scientific Projects Database; Computer-Aided Design; Computing Methodologies; Data; Development; Diffusion; Educational workshop; Environment; Feedback; Funding; Grant; Hand; High Performance Computing; Imagery; Individual; Institutes; Institution; Laboratories; Modeling; Monte Carlo Method; Nature; Neurobiology; Reaction; Research; Research Personnel; Resources; Schedule; Science; Shapes; Signal Transduction; Solutions; Source; Supercomputing; Surface; System; United States National Institutes of Health; base; biomedical resource; design; instructor; lectures; model design; models and simulation; neurotransmission; reconstruction; simulation; theories; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. his workshop will cover theory and practice for the design and simulation of models focused on diffusion-reaction systems such as neurotransmission, signaling cascades, and other forms of biochemical networks (e.g., Coggan et al., 2005, Science 309:446-451; He et al., 2006, Nature 444:102-105). Current versions of the MCell/DReAMM simulation environment (www.mcell.psc.edu and www.mcell.cnl.salk.edu) will be introduced, including new Monte Carlo methods for 3-D simulation of reactions in solution and on arbitrarily shaped biological surfaces, as well as new tools for model design and visualization. Models created from both anatomical reconstruction tools and computer-aided design tools will be covered. Based on feedback from a similar highly successful workshop in June 2006, this workshop has been extended to five full days, and attendees will be strongly encouraged to bring ideas/data for their own simulation projects. The daily schedule will include theoretical and practical lectures, instructor-guided hands-on tutorials, and opportunities for one-on-one interaction with the instructors on individual project development. The primary instructors will be Joel Stiles (National Resource for Biomedical Supercomputing) and Thomas Bartol (Computational Neurobiology Laboratory, The Salk Institute), the original developers of MCell and DReAMM.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 他的研讨会将涵盖理论和实践的设计和模拟模型的重点是扩散反应系统，如神经传递，信号级联，和其他形式的生化网络（例如，Coggan等人，2005，Science 309：446-451; He等人，2006，Nature 444：102-105）。将介绍MCell/DReAMM模拟环境（www.mcell.psc.edu和www.mcell.cnl.salk.edu）的当前版本，包括用于溶液中和任意形状生物表面上反应的3-D模拟的新Monte Carlo方法，以及用于模型设计和可视化的新工具。将涵盖从解剖重建工具和计算机辅助设计工具创建的模型。根据2006年6月一次类似的非常成功的讲习班的反馈，这次讲习班已延长到五天，并将大力鼓励与会者为自己的模拟项目带来想法/数据。每天的时间表将包括理论和实践讲座，导师指导的实践教程，以及与导师就个人项目开发进行一对一互动的机会。主要讲师将是Joel Stiles（国家生物医学超级计算资源）和托马斯Bartol（Salk研究所计算神经生物学实验室），MCell和DReAMM的原始开发者。