COURSEWORK: BIOL 4112/4113 BIOINFORMATICS SPRING 2009

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 生物信息学是生物学和计算机科学相结合的一个跨学科领域。本课程强调如何使用计算工具来解决重要的生物/生物医学问题。这是一个动手，实用的方法来分析大分子，推断结构，生理功能和进化历史。将介绍各种计算工具和生物/生物医学数据库。 学生将 + 获得各种生物/生物医学数据库的知识。 + 知道如何应用各种计算工具来解决基本的生物学/生物医学问题 + 理解计算方法的基本原理，局限性

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Bioinformatics is an interdisciplinary field which merges biology and computer sciences. This course emphasizes how to use computational tools to solve significant biological/biomedical problems. This is a hands-on, practical approach to analyze large molecules, to infer the structure, physiological function and evolutionary history. Various computational tools and biological/biomedical databases will be introduced. Students will + gain knowledge of various biological/biomedical databases. + know how to apply various computational tools to address fundamental biological/biomedical problems + understand basic principles underlying computational approaches, limitations