EVALUATION OF QUALITY OF MACROMOLECULAR CRYSTALS

高分子晶体的质量评价

• 批准号: 7956841
• 负责人: VUKICA SRAJER
• 金额: $ 3.77万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956841
• 关键词: Anodes; Computer Retrieval of Information on Scientific Projects Database; Data; Evaluation; Funding; Grant; Home environment; Image; Institution; Process; Research; Research Personnel; Resources; Roentgen Rays; Source; Speed; Synchrotrons; Testing; Training; United States National Institutes of Health; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. BioCARS is offering crystal evaluation sessions where beamtime is allocated on a short notice to local user groups to test and evaluate their new crystals. A critical part of any crystallographic project is optimization and evaluation of crystal quality and new crystal forms. This process is usually painstakingly done on a rotating anode at the home institution. We propose to continue with offering such evaluation at the Sector 14. Very intense synchrotron X-ray source provides important advantages: it greatly speeds up the process, obtained diffraction images provide better indication of crystal quality and testing of small or weakly diffracting crystals becomes possible. Our previous evaluation sessions have proven very popular and valuable to local users. We are offering these sessions only to already registered APS users with current training, so some of the data collected under this proposal could also be associated with other general user proposals.

这个子项目是众多研究子项目之一