CRYSTAL SCREENING
晶体筛选
基本信息
- 批准号:7956831
- 负责人:
- 金额:$ 4.24万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-08-01 至 2010-07-31
- 项目状态:已结题
- 来源:
- 关键词:AnodesClinicCollectionComputer Retrieval of Information on Scientific Projects DatabaseDataFundingGrantGrowthHome environmentHuman ResourcesImageInstitutionProcessResearchResearch PersonnelResourcesSamplingScreening procedureSeriesSourceSpeedTrainingUnited States National Institutes of Healthstructural biologysynchrotron radiation
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
BioCARS is offering a series of crystal screening sessions, where local user groups are able to evaluate new crystals at short notice. An important part of crystal growth and optimization is evaluating crystal quality and new crystal forms. This process is usually painstakingly done on a rotating anode at the home institution. We propose to do this screening at the APS because of the increased beam intensity and quality of synchrotron radiation. Besides greatly speeding up the process, diffraction images obtained at the APS should give a better indication of crystal quality.
Our previous clinics have proven very popular and useful to local users. We are only offering these screening sessions to registered APS users with current training, so some of the data collected under this proposal could also be associated with other general user proposals. Absolutely no hazardous samples or materials will be allowed given the collection of different user groups and short notice for addition of new samples and personnel.
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目和
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
BioCARS提供了一系列的晶体筛选会议,在那里当地的用户群体能够在短时间内评估新的晶体。 晶体生长和优化的一个重要部分是评估晶体质量和新的晶体形式。 这个过程通常是在家庭机构的旋转阳极上辛苦完成的。 我们建议在APS进行这种筛选,因为同步辐射的光束强度和质量有所提高。 除了大大加快过程之外,在APS获得的衍射图像应该更好地指示晶体质量。
我们以前的诊所已被证明是非常受欢迎和有用的本地用户。 我们仅向当前接受过培训的注册APS用户提供这些筛选会话,因此根据此提案收集的一些数据也可能与其他一般用户提案相关联。 考虑到不同用户组的收集以及添加新样本和人员的短时间通知,绝对不允许使用危险样本或材料。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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VUKICA SRAJER其他文献
VUKICA SRAJER的其他文献
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{{ truncateString('VUKICA SRAJER', 18)}}的其他基金
WORKSHOP ON TIME-RESOLVED MACROMOLECULAR CRYSTALLOGRAPHY AT BIOCARS
BIOCARS 时间分辨高分子晶体学研讨会
- 批准号:
7956820 - 财政年份:2009
- 资助金额:
$ 4.24万 - 项目类别:
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