SEQUENCE DETERMINANTS OF PROTEIN STRUCTURE AND FUNCTION

蛋白质结构和功能的序列决定因素

• 批准号: 7955082
• 负责人: Robert T Sauer
• 金额: $ 0.25万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7955082
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Enzymes; Funding; Grant; Institution; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; protein structure function; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Under the auspices of this project, we are studying how AAA+ enzymes including ClpXP, HslUV, and Lon catalyze ATP-dependent denaturation of specific target proteins and subsequent degradation.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在该项目的支持下，我们正在研究包括ClpXP、HslUV和Lon在内的AAA+酶如何催化特定目标蛋白的依赖于ATP的变性和随后的降解。