TMRNA MEDIATED TAGGING AND PROTEIN DEGRADATION

TRNA 介导的标记和蛋白质降解

• 批准号: 8169268
• 负责人: Robert T Sauer
• 金额: $ 0.52万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169268
• 关键词: Adaptor Signaling Protein; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Mediating; Molecular; Peptide Hydrolases; Research; Research Personnel; Resources; Signal Transduction; Source; United States National Institutes of Health; protein aminoacid sequence; protein degradation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are determining mechanisms by which peptide sequences and adaptor proteins target proteins for degradation by bacterial proteases and elucidating the molecular signals and mechanisms that regulate allosteric PDZ-proteases.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 我们正在确定肽序列和衔接蛋白通过细菌蛋白酶降解并阐明调节变构PDZ-蛋白酶的分子信号和机制来降解的机制。