COBRE: LOUISVILLE RES FOUND INC: CORE E: BIOPHYSICAL FACILITY

COBRE：路易斯维尔 RES FOUND INC：核心 E：生物物理设施

• 批准号: 7959812
• 负责人: Jonathan B. CHAIRES
• 金额: $ 5.28万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959812
• 关键词: Area; Arts; Biophysics; Calorimetry; Cancer Center; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Data Analyses; Electronics; Floor; Funding; Grant; Institution; Kinetics; Laboratories; Methods; Molecular Models; Molecular Target; Research; Research Personnel; Resources; Source; Spectrum Analysis; Training; United States National Institutes of Health; drug discovery; experience; instrumentation; molecular modeling; square foot; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Biophysics Core Facility is located on the fourth floor of the Brown Cancer Center in a newly renovated 504 square-foot laboratory. This state-of-the-art facility provides the capability to perform calorimetry, electronic spectroscopy, rapid kinetics and hydrodynamics determinations. Expertise is provided by the director, Dr. J. Brad Chaires, and by Dr. Nichola Garbett, the facility manager, both of whom have considerable experience in this area. In addition to the instrumentation, this facility provides training in biophysical methods and data analysis and is integrated with the molecular modeling and structural biology cores at the Brown Cancer Center to enhance drug discovery efforts. The Biophysics Core Facility provides a unique resource to all MT-COBRE investigators.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 生物物理学核心设施位于布朗癌症中心四楼一个新装修的504平方英尺的实验室。 这一最先进的设施提供了进行量热法、电子光谱法、快速动力学和流体力学测定的能力。 主管J.布拉德·凯尔斯博士和设施经理尼古拉·加贝特博士提供了专业知识，他们在这方面都有相当丰富的经验。 除了仪器，该设施还提供生物物理方法和数据分析方面的培训，并与布朗癌症中心的分子建模和结构生物学核心相结合，以加强药物发现工作。 生物物理学核心设施为所有MT-COBRE研究人员提供了独特的资源。