COBRE: LOUISVILLE RES FOUND INC: CORE E: BIOPHYSICAL FACILITY

COBRE：路易斯维尔 RES FOUND INC：核心 E：生物物理设施

• 批准号: 8360671
• 负责人: Jonathan B. CHAIRES
• 金额: $ 10.78万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360671
• 关键词: Area; Biophysics; Calorimetry; Cancer Center; Centers of Research Excellence; Core Facility; Data Analyses; Electronics; Floor; Funding; Grant; Kinetics; Laboratories; Methods; Molecular Models; Molecular Target; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Research Personnel; Resources; Source; Spectrum Analysis; Training; United States National Institutes of Health; cost; drug discovery; experience; instrumentation; molecular modeling; square foot; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Biophysics Core Facility is located on the fourth floor of the Brown Cancer Center in a newly renovated 504 square-foot laboratory. This state-of-the-art facility provides the capability to perform calorimetry, electronic spectroscopy, rapid kinetics and hydrodynamics determinations. Expertise is provided by the director, Dr. J. Brad Chaires, and by Dr. Nichola Garbett, the facility manager, both of whom have considerable experience in this area. In addition to the instrumentation, this facility provides training in biophysical methods and data analysis and is integrated with the molecular modeling and structural biology cores at the Brown Cancer Center to enhance drug discovery efforts. The Biophysics Core Facility provides a unique resource to all MT-COBRE investigators.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 生物物理学核心设施位于布朗癌症中心四楼新装修的 504 平方英尺实验室内。 这种最先进的设施能够进行量热、电子光谱、快速动力学和流体动力学测定。 主任 J. Brad Chaires 博士和设施经理 Nichola Garbett 博士提供专业知识，两人在该领域都拥有丰富的经验。 除了仪器之外，该设施还提供生物物理方法和数据分析方面的培训，并与布朗癌症中心的分子建模和结构生物学核心相集成，以加强药物发现工作。 生物物理学核心设施为所有 MT-COBRE 研究人员提供了独特的资源。