COBRE: LSU: NEUROCHEM OF LIPID MESSENGERS CORE RESOURCE MODULE: RADIOCHEM TECH
COBRE: LSU: NEUROCHEM OF LIPID MESSENGERS CORE RESOURCE MODULE: RADIOCHEM TECH
批准号:
7959412
负责人:
Nicolas G. Bazan
金额:
$11.2万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-02-01 至 2010-01-31
关键词:
Centers of Research ExcellenceComputer Retrieval of Information on Scientific Projects DatabaseDataFundingGrantHigh Pressure Liquid ChromatographyHousingInstitutionLipidsLouisianaMeasuresMentorsNeurosciencesParticipantResearchResearch PersonnelResourcesSecond Messenger SystemsSourceTechniquesUnited States National Institutes of Healthexperienceinstrumentlipid metabolismneurochemistryprogramsradiochemicalresearch studysecond messenger
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
脂质信使核心资源模块(NCLM)的神经化学由维克托·马切塞利(Victor Marcheselli)领导,他在分析脂质第二信使方面拥有丰富的经验。NCLM允许核心参与者通过放射化学和色谱技术(TLC、HPLC和GLC)测量内源性脂质信使的数量,并跟踪刺激后脂质介质的新陈代谢。该核心还在数据解释方面提供技术支持和协助。CORE配备了一个新的LC-MS/MS,部分是用科布雷请求的资金购买的,部分是通过与路易斯安那州立大学的匹配资金购买的。该仪器可以识别在拟议项目的实验中识别和研究的新的生物活性脂类。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
The Neurochemistry of Lipid Messengers Core Resource Module (NCLM) is directed by Victor Marcheselli, an investigator who has extensive experience in analysis of lipid second messengers. The NCLM allows core participants to measure by radiochemical and chromatographic techniques (TLC, HPLC and GLC) quantities of endogenous lipid messengers as well as to follow the metabolism of lipid mediatorss after stimulation. The core also provides technical support and assistance in interpretation of the data. The core houses a new LC-MS/MS that was purchased in part with funds requested in the COBRE and in part by matching funds from LSU. This instrument allows identification of new bioactive lipids identified and studied in the experiments of the proposed projects.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Docosanoids modulate homeostasis and cell survival after ischemic stroke
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批准号:10221785
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项目类别:
-
资助金额:$32.87万
-
财政年份:2019
-
负责人:Nicolas G. Bazan
-
依托单位:
Docosanoids modulate homeostasis and cell survival after ischemic stroke
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批准号:10395594
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项目类别:
-
资助金额:$32.87万
-
财政年份:2019
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负责人:Nicolas G. Bazan
-
依托单位:
Docosanoids modulate homeostasis and cell survival after ischemic stroke
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批准号:10606600
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项目类别:
-
资助金额:$32.87万
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财政年份:2019
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负责人:Nicolas G. Bazan
-
依托单位:
Docosanoids modulate homeostasis and cell survival after ischemic stroke
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批准号:9815688
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项目类别:
-
资助金额:$33.89万
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财政年份:2019
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负责人:Nicolas G. Bazan
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依托单位:
Novel combinatory therapy for experimental ischemic stroke
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批准号:10330435
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项目类别:
-
资助金额:$32.77万
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财政年份:2018
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负责人:Nicolas G. Bazan
-
依托单位:
Novel combinatory therapy for experimental ischemic stroke
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批准号:10093153
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项目类别:
-
资助金额:$32.77万
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财政年份:2018
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负责人:Nicolas G. Bazan
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依托单位:
Mentoring Neuroscience in Louisiana: A Biomedical Program to Enhance Neuroscience
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批准号:8853292
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项目类别:
-
资助金额:$103.12万
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财政年份:2012
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负责人:Nicolas G. Bazan
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依托单位:
Mentoring Neuroscience in Louisiana: A Biomedical Program to Enhance Neuroscience
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批准号:9068162
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项目类别:
-
资助金额:$103.12万
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财政年份:2012
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负责人:Nicolas G. Bazan
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依托单位:
Administrative Core
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批准号:8479230
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项目类别:
-
资助金额:$45.02万
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财政年份:2012
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负责人:Nicolas G. Bazan
-
依托单位:
Mentoring Neuroscience in Louisiana: A Biomedical Program to Enhance Neuroscience
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批准号:8536885
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项目类别:
-
资助金额:$99.51万
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财政年份:2012
-
负责人:Nicolas G. Bazan
-
依托单位:
Mentoring Neuroscience in Louisiana: A Biomedical Program to Enhance Neuroscience
-
批准号:8668105
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项目类别:
-
资助金额:$103.12万
-
财政年份:2012
-
负责人:Nicolas G. Bazan
-
依托单位:
Mentoring Neuroscience in Louisiana: A Biomedical Program to Enhance Neuroscience
-
批准号:8305279
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项目类别:
-
资助金额:$103.12万
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财政年份:2012
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负责人:Nicolas G. Bazan
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依托单位:
COBRE: LSU: ADMIN, MENTOR, RECRUIT & EVAL CORE: STROKE, NEURODEGEN DIS, BEHAV
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批准号:8359597
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项目类别:
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资助金额:$37.13万
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财政年份:2011
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负责人:Nicolas G. Bazan
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依托单位:
microRNA (miRNA) signaling in Alzheimer's disease(AD)
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批准号:9916675
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项目类别:
-
资助金额:$36.5万
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财政年份:2011
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负责人:Nicolas G. Bazan
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依托单位:
COBRE: LSU: ADMIN, MENTOR, RECRUIT & EVAL CORE: STROKE, NEURODEGEN DIS, BEHAV
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批准号:8167385
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项目类别:
-
资助金额:$72.3万
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财政年份:2010
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负责人:Nicolas G. Bazan
-
依托单位:
COBRE: LSU: ADMIN, MENTOR, RECRUIT & EVAL CORE: STROKE, NEURODEGEN DIS, BEHAV
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批准号:7959410
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项目类别:
-
资助金额:$98.3万
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财政年份:2009
-
负责人:Nicolas G. Bazan
-
依托单位:
Mechanism of action of omega-3 fatty acids in brain injury
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批准号:7855624
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项目类别:
-
资助金额:$141.82万
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财政年份:2009
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负责人:Nicolas G. Bazan
-
依托单位:
Mechanism of action of omega-3 fatty acids in brain injury
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批准号:7933693
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项目类别:
-
资助金额:$140.62万
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财政年份:2009
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负责人:Nicolas G. Bazan
-
依托单位:
COBRE: LSU: MOLECUL NEUROBIOL CORE RESOURCE MODULE: TRANSGENIC KNOCKOUT ANIMALS
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批准号:7959411
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项目类别:
-
资助金额:$13.86万
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财政年份:2009
-
负责人:Nicolas G. Bazan
-
依托单位:
Mentoring Neuroscience in Louisiana: A Biomedical Program to Enhance Neuroscience
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批准号:7848634
-
项目类别:
-
资助金额:$19.08万
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财政年份:2009
-
负责人:Nicolas G. Bazan
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依托单位: