BEHAVIORAL MANAGEMENT OF DELETERIOUS AGGRESSION IN RHESUS MACAQUES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在NIH/NCRR赞助的国家灵长类动物研究中心的繁殖项目中，恒河猴被安置在模拟自然、社会和环境特征的大型户外畜栏中，以多雌-多母的社会群体形式饲养 这是该物种的特征，提高了它们的繁殖性能和心理健康。尽管这种自然主义的社会住房很重要，但社会住房猕猴最棘手的问题之一是它们倾向于自发地发起有害的攻击。该项目的长期目标是降低圈养繁殖的恒河猴群体的有害攻击率。这一特定应用的目的是通过开发一套预测模型来增强当前的行为管理技术，该模型用于预测群居恒河猴中导致有害攻击和基于攻击的发病率和死亡率的群组内社会和群组级别的管理因素。使用Logistic正态回归和社会网络分析的多元统计模型将建立在群体管理因素之间的纵向(时间)关系，如年龄/性别构成和母系结构，群体内社会因素如从属和支配活动模式，以及猕猴社会群体内的攻击和随后的伤害水平。我们的理论基础是，如果我们对这些社会和群体管理因素有更深入的了解，我们将能够确定关键的网络措施，使我们能够在短期内防止严重的攻击事件和暴发，并通过有益的管理实践，在长期内降低恒河猴繁殖群体中基于攻击的发病率和死亡率。开发有益的管理实践，减少恒河猴繁育群体中基于攻击性的发病率和死亡率，将通过提高繁育群体中恒河猴的健康和福利来促进公共健康，这些繁育群体为对非人类灵长类动物进行生物医学研究提供关键的动物资源。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In the NIH/NCRR sponsored breeding programs of the National Primate Research Centers, rhesus macaques are housed in multimale-multifemale social groups in large outdoor corrals which simulates the natural social and environmental features characteristic of the species, enhancing their reproductive performance as well as their psychological well-being. Despite the importance of this naturalistic social housing, one of the most difficult problems in socially-housed macaques is their propensity for spontaneous bouts of deleterious aggression. The long-term goal of this project is to reduce the rates of deleterious aggression in captive breeding colonies of rhesus macaques. The objective of this particular application is to enhance current behavioral management techniques by developing a set of predictive models of the within group social and group-level management factors that lead to deleterious aggression and aggression-based morbidity and mortality in group-housed rhesus macaques. Multivariate statistical models using logistic normal regression and social network analysis will be developed on the longitudinal (temporal) relationship among group management factors such as age/sex composition and matriline configuration, within-group social factors such as affiliative and dominance activity patterns and levels of aggression and subsequent wounding within rhesus social groups. Our rationale is that if we gain greater insight into these social and group management factors, we will be able to identify key network measures that will allow us to prevent severe aggression events and outbreaks in the short-term and beneficial management practices that will reduce aggression-based morbidity and mortality in the long-term in rhesus macaque breeding colonies. Development of beneficial management practices that reduce aggression-based morbidity and mortality in rhesus breeding groups will contribute to public health by enhancing the health and welfare of rhesus macaques in breeding colonies that provide the animal resources critical for conducting biomedical research on nonhuman primates.