BEHAVIORAL MANAGEMENT OF DELETERIOUS AGGRESSION IN RHESUS MACAQUES

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 在NIH/NCRR资助的国家灵长类动物研究中心的繁殖计划中，恒河猴被安置在大型户外围栏中的多雄性多雌性社会群体中，模拟自然的社会和环境特征 这是一个物种的特征，提高他们的生殖能力以及他们的心理健康。尽管这种自然的社会住房的重要性，在社会住房猕猴最困难的问题之一是他们的倾向，自发的有害的攻击。该项目的长期目标是降低圈养繁殖群中恒河猴的有害攻击率。这个特定的应用程序的目的是提高目前的行为管理技术，通过开发一组预测模型的组内的社会和组级管理因素，导致有害的侵略和侵略为基础的发病率和死亡率组圈养的恒河猴。使用逻辑正态回归和社会网络分析的多变量统计模型将开发组管理因素之间的纵向（时间）关系，如年龄/性别组成和母系配置，组内的社会因素，如亲和和优势活动模式和水平的攻击和随后的伤害在恒河猴社会群体。我们的基本原理是，如果我们更深入地了解这些社会和群体管理因素，我们将能够确定关键的网络措施，使我们能够在短期内防止严重的攻击事件和爆发，并采取有益的管理措施，以减少恒河猴繁殖群体长期的攻击性发病率和死亡率。发展有益的管理实践，减少侵略为基础的发病率和死亡率在恒河猴繁殖群体将有助于公共卫生，提高健康和福利的恒河猴繁殖殖民地提供的动物资源进行生物医学研究的非人灵长类动物。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In the NIH/NCRR sponsored breeding programs of the National Primate Research Centers, rhesus macaques are housed in multimale-multifemale social groups in large outdoor corrals which simulates the natural social and environmental features characteristic of the species, enhancing their reproductive performance as well as their psychological well-being. Despite the importance of this naturalistic social housing, one of the most difficult problems in socially-housed macaques is their propensity for spontaneous bouts of deleterious aggression. The long-term goal of this project is to reduce the rates of deleterious aggression in captive breeding colonies of rhesus macaques. The objective of this particular application is to enhance current behavioral management techniques by developing a set of predictive models of the within group social and group-level management factors that lead to deleterious aggression and aggression-based morbidity and mortality in group-housed rhesus macaques. Multivariate statistical models using logistic normal regression and social network analysis will be developed on the longitudinal (temporal) relationship among group management factors such as age/sex composition and matriline configuration, within-group social factors such as affiliative and dominance activity patterns and levels of aggression and subsequent wounding within rhesus social groups. Our rationale is that if we gain greater insight into these social and group management factors, we will be able to identify key network measures that will allow us to prevent severe aggression events and outbreaks in the short-term and beneficial management practices that will reduce aggression-based morbidity and mortality in the long-term in rhesus macaque breeding colonies. Development of beneficial management practices that reduce aggression-based morbidity and mortality in rhesus breeding groups will contribute to public health by enhancing the health and welfare of rhesus macaques in breeding colonies that provide the animal resources critical for conducting biomedical research on nonhuman primates.