课题基金 / 基金详情

ARRA ^ Clinical Studies of Vaccines for Pandemic H1N1 Influenza

ARRA ^ Clinical Studies of Vaccines for Pandemic H1N1 Influenza
ARRA ^ 大流行性 H1N1 流感疫苗的临床研究
批准号：
7964773
负责人：
Kanta Subbarao
金额：
$4.23万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7964773
关键词：
AmericanAttenuatedAttenuated Live Virus VaccineAvian Influenza A VirusBiological AssayCaliforniaCenters for Disease Control and Prevention (U.S.)Clinical ResearchClinical TrialsDiseaseEquilibriumFamily suidaeGene CombinationsGene ProteinsGenesGeneticGoalsHemagglutinationHemagglutininHumanImmune responseInfectionInfluenzaInfluenza A Virus, H1N1 SubtypeLicensingLifeMembrane GlycoproteinsNeuraminidasePorcine Influenza A VirusReportingSimian B diseaseUnited StatesVaccinesVirusVirus DiseasesWorld Health Organizationattenuationbasegenetic analysisimmunogenicityinfluenza virus vaccinenovelpandemic diseasepandemic influenzapandemic preparednesspreclinical studyprogramsresponsevaccine candidatevaccine development

项目摘要

项目成果

Kanta Subbarao的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
An appropriate vaccine is essential for a global pandemic preparedness and response. Hemagglutination inhibition assays reveal that the 2009 pandemic H1N1 viruses are antigenically homogeneous and distinct from currently circulating seasonal H1N1 viruses. Based on antigenic and genetic analysis and epidemiologic information, the WHO selected the A/California/7/2009 (H1N1) virus as the reference virus for vaccine development. We will evaluate the immunogenicity and infectivity of the live attenuated reassortant H1N1 virus containing the surface glycoproteins from the California/7/2009 (H1N1) virus and internal protein genes from the A/Ann Arbor/6/60 cold-adapted (ca) virus in clinical trials.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
EVAL. OF VACCINE AGAINST HIGHLY PATHOGENIC INFLUENZA A(H5N1) VIRUS IN MACAQUES
Vaccines for Pandemic Influenza
Preclinical Studies of Vaccines for Pandemic Influenza
Clinical Studies of Vaccines for Pandemic Influenza
海外基金