Immune regulation, effector function and therapy

免疫调节、效应器功能和治疗

• 批准号: nhmrc : 1013667
• 负责人: A/Pr Michael Kershaw
• 金额: $ 901.53万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Program Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/immune-regulation-effector-function-therapy/109737
• 关键词: Immune; regulation; effector; function; therapy

We seek to understand how white blood cells detect and destroy disease, and how molecules of the immune system punch holes in diseased cells. We wish to learn how cancer can sometimes evade the immune system. Our work will also find out how some common treatments for cancer, like chemotherapy, can be used to boost the immune system and eliminate tumours. Through knowledge gained from these studies, we aim to develop new therapies that can help patients with devastating diseases like cancer.

我们试图了解白色血细胞如何检测和破坏疾病，以及免疫系统的分子如何在病变细胞中穿孔。我们希望了解癌症有时如何逃避免疫系统。我们的工作还将发现一些常见的癌症治疗方法，如化疗，可以用来增强免疫系统和消除肿瘤。通过从这些研究中获得的知识，我们的目标是开发新的疗法，可以帮助癌症等毁灭性疾病的患者。