Generating Stronger and Smarter T Cells for Cancer Therapy

生成更强大、更智能的 T 细胞用于癌症治疗

• 批准号: nhmrc : 1006188
• 负责人: A/Pr Michael Kershaw
• 金额: $ 20.69万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/generating-stronger-smarter-cancer-therapy/109152
• 关键词: Generating; Stronger; Smarter; Cells; Cancer

White blood cells from cancer patients can be modified in the laboratory to react against tumours. These cells can then be given back to the patient, which can sometimes cause cancer regression. However, often the white blood cells lack strength, or they lack the ability to distinguish between tumour and normal tissues of the body. In this project we seek to make stronger and smarter white blood cells that can deliver a lethal hit against tumours without damaging essential organs of the body.

来自癌症患者的白色血细胞可以在实验室中进行修饰，以对抗肿瘤。然后可以将这些细胞还给患者，这有时会导致癌症消退。然而，通常白色血细胞缺乏强度，或者它们缺乏区分身体的肿瘤和正常组织的能力。在这个项目中，我们寻求制造更强大、更聪明的白色血细胞，这种血细胞可以对肿瘤进行致命打击，而不会损害身体的重要器官。