North Carolina A&T University-Wake Forest Cancer Center partnership (1of 2)

这份P20提案提出了维克森林大学之间的研究和教育伙伴关系 综合癌症中心(WFUCCC)和北卡罗来纳州生物和化学系 农业科技大学(NC A&T)。该伙伴关系的目标是：(1)促进癌症 WFUCCC与NC A&T之间的研究合作，特别是专注于癌症差异的研究 通过与NCA&T合作，促进少数族裔癌症研究人员的职业发展 (2)培养少数族裔人士取得癌症生物学博士学位的兴趣 北卡罗来纳州农工学院的本科生和硕士研究生为实现第一个目标，P20将提供试点 两个合作研究项目的资金：(1)WFUCCC的Suzy Torti博士和Yong Chen博士将指导和 与北卡罗来纳大学化学助理教授Marion Franks博士合作进行一个项目，以合成和 评估新的亚苄基化合物作为前列腺癌化学预防药物；(2)沃尔德马尔·德宾斯基博士， WFUCCC脑瘤中心将指导并与助理教授Patrick Martin博士合作 北卡罗来纳大学生物学教授参与了一项了解转录因子Fral在胶质母细胞瘤细胞中的作用的项目 机动性和对疗法的抵抗力..要实现第二个目标：(1)选择Rise、Marc和Blend NC A&T的项目本科生将参加湿实验室、计算生物学或健康差距 外展项目由WFUCCC教职员工指导；(2)每个试点项目团队将至少选出一名NC A&T 硕士研究生参与该项目。将向学生提供继续的选项 作为西外癌症生物学的博士生参与这些项目；(3)西外大学和北卡罗来纳大学的教职员工将 目前合作开发癌症基因组学和癌症动物模型的教学模块 在北卡罗来纳州A&T正在进行的课程工作在P20结束时预计：(1)Franks博士和Martin博士以及 他们的WFUCCC合作者将编写联合ROL；(2)WFUCCC和NC A&T将编写R25 桥接申请，以支持西弗吉尼亚大学癌症生物学博士项目的NC A&T学生入学。

This P20 proposal presents a research and educational partnership between the Wake Forest University Comprehensive Cancer Center (WFUCCC) and the Departments of Biology and Chemistry of North Carolina Agricultural and Technical University (NC A&T). The objectives of the partnership are: (1) to foster cancer research collaborations between WFUCCC and NC A&T, especially research focused on cancer disparities and to facilitate the career development of minority cancer research faculty at NC A&T through collaborations with and mentoring provided by the WFUCCC; (2) to foster interest in obtaining a PhD in cancer biology among minority undergraduate and Master's degree students at NC A&T. To achieve the first objective, the P20 will provide pilot funds for two collaborative research projects: (1) Drs. Suzy Torti and Yong Chen of the WFUCCC will mentor and collaborate with Dr. Marion Franks, Assistant Professor of Chemistry at NC A&T, on a project to synthesize and evaluate novel benzylidenes as prostate cancer chemopreventive agents; (2) Dr. Waldemar Debinski, Director of the Brain Tumor Center of the WFUCCC, will mentor and collaborate with Dr. Patrick Martin, Assistant Professor of Biology at NC A&T on a project to understand the role of transcription factor Fral in glioblastoma cell mobility and resistance to therapeutics.. To achieve the second objective: (1) Selected RISE, MARC, and BLEND program undergraduates at NC A&T will participate in wet laboratory, computational biology, or health disparity outreach projects mentored by WFUCCC faculty; (2) Each pilot project team will select at least one NC A&T Master's degree student to participate in the project. The students will be offered the option of continued participation in the projects as PhD students in Cancer Biology at WFU; (3) WFUCCC and NC A&T faculty will collaborate to develop didactic teaching modules in cancer genomics and animal models of cancer for currently ongoing coursework at NC A&T. By the conclusion of the P20 it is expected that: (1) Drs. Franks and Martin and their WFUCCC collaborators will be writing joint ROls; (2) The WFUCCC and NC A&T will be writing an R25 bridge application to support enrollment of NC A&T students in the PhD program in Cancer Biology at WFU.