North Carolina A&T University-Wake Forest Cancer Center partnership (1of 2)

北卡罗来纳州A

• 批准号: 8136131
• 负责人: STEVEN A AKMAN
• 金额: $ 25.62万
• 依托单位: NORTH CAROLINA AGRI & TECH ST UNIV
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-25 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8136131
• 关键词: Achievement; African American; Agriculture; Animal Cancer Model; Biology; Brain Neoplasms; CCL7 gene; Cancer Biology; Cancer Center; Cell Mobility; Chemistry; Chemopreventive Agent; Collaborations; Comprehensive Cancer Center; Comprehensive Cancer Center of Wake Forest University; Computational Biology; Development; Doctor of Philosophy; Educational process of instructing; Enrollment; Faculty; Fostering; Funding; Glioblastoma; Historically Black Colleges and Universities; Joints; Laboratories; Malignant Neoplasms; Malignant neoplasm of prostate; Master' s Degree; Mentors; Minority; North Carolina; Pilot Projects; Research; Research Project Grants; Resistance; Role; Scientist; Students; Therapeutic; Training; Universities; Writing; anticancer research; cancer genomics; cancer health disparity; career; career development; design; forest; health disparity; interest; novel; outreach; professor; programs; transcription factor; university student

This P20 proposal presents a research and educational partnership between the Wake Forest University Comprehensive Cancer Center (WFUCCC) and the Departments of Biology and Chemistry of North Carolina Agricultural and Technical University (NC A&T). The objectives of the partnership are: (1) to foster cancer research collaborations between WFUCCC and NC A&T, especially research focused on cancer disparities and to facilitate the career development of minority cancer research faculty at NC A&T through collaborations with and mentoring provided by the WFUCCC; (2) to foster interest in obtaining a PhD in cancer biology among minority undergraduate and Master's degree students at NC A&T. To achieve the first objective, the P20 will provide pilot funds for two collaborative research projects: (1) Drs. Suzy Torti and Yong Chen of the WFUCCC will mentor and collaborate with Dr. Marion Franks, Assistant Professor of Chemistry at NC A&T, on a project to synthesize and evaluate novel benzylidenes as prostate cancer chemopreventive agents; (2) Dr. Waldemar Debinski, Director of the Brain Tumor Center of the WFUCCC, will mentor and collaborate with Dr. Patrick Martin, Assistant Professor of Biology at NC A&T on a project to understand the role of transcription factor Fral in glioblastoma cell mobility and resistance to therapeutics.. To achieve the second objective: (1) Selected RISE, MARC, and BLEND program undergraduates at NC A&T will participate in wet laboratory, computational biology, or health disparity outreach projects mentored by WFUCCC faculty; (2) Each pilot project team will select at least one NC A&T Master's degree student to participate in the project. The students will be offered the option of continued participation in the projects as PhD students in Cancer Biology at WFU; (3) WFUCCC and NC A&T faculty will collaborate to develop didactic teaching modules in cancer genomics and animal models of cancer for currently ongoing coursework at NC A&T. By the conclusion of the P20 it is expected that: (1) Drs. Franks and Martin and their WFUCCC collaborators will be writing joint ROls; (2) The WFUCCC and NC A&T will be writing an R25 bridge application to support enrollment of NC A&T students in the PhD program in Cancer Biology at WFU.

这个P20提案提出了维克森林大学之间的研究和教育伙伴关系 综合癌症中心（WFUCCC）和北卡罗来纳州生物系和化学系 农业技术大学（NC A&T）该伙伴关系的目标是：（1）促进癌症 WFUCCC和NC A&T之间的研究合作，特别是关注癌症差异的研究， 促进少数民族癌症研究教师在NC A&T的职业发展，通过与 WFUCCC提供的指导;（2）培养少数民族获得癌症生物学博士学位的兴趣 NC A&T的本科生和硕士生。为了实现第一个目标，P20将提供试点 两个合作研究项目的资金：（1）WFUCCC的Suzy Torti和Yong Chen博士将指导和 与NC A&T化学助理教授Marion Franks博士合作，进行一个项目， 评估新型亚苄基作为前列腺癌化学预防剂;（2）Waldemar Debinski博士， WFUCCC的脑肿瘤中心，将指导和合作博士帕特里克马丁，助理教授 在NC A&T的一个项目中，了解转录因子Fral在胶质母细胞瘤细胞中的作用， 流动性和对治疗的抵抗力。实现第二个目标：（1）选择RISE、MARC和BLEND NC A&T的计划本科生将参加湿实验室，计算生物学或健康差异 由WFUCCC教师指导的外展项目;（2）每个试点项目团队将选择至少一个NC A&T 硕士研究生参与该项目。学生们可以选择继续 作为WFU癌症生物学博士生参与项目;（3）WFUCCC和NC A&T教师将 合作开发癌症基因组学和癌症动物模型的教学模块， 在NC A&T进行的课程。到20国集团结束时，预计：（1）弗兰克斯和马丁博士， 他们的WFUCCC合作者将编写联合ROLS;（2）WFUCCC和NC A&T将编写R25 桥梁应用程序，以支持NC A&T学生在癌症生物学博士课程在WFU招生。