Using multiple datasets to examine youth psychiatric diagnosis

使用多个数据集检查青少年精神病学诊断

基本信息

批准号：
8063907
负责人：
Prudence Winslow Fisher
金额：
$ 66.09万
依托单位：
NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-08-01 至 2013-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8063907
关键词：
10 year old Address Adjustment Disorders Adolescent Adolescent Psychiatry Adopted Adult Advisory Committees Affect Age Age of Onset Algorithms American Psychiatric Association Antisocial Personality Disorder Anxiety Anxiety Disorders Archives Attention deficit hyperactivity disorder Behavior Categories Characteristics Child Child Psychiatry Childhood Classification Clinical Communities Comorbidity Conduct Disorder Consensus DSM-III DSM-IV DSM-V Data Data Aggregation Data Set Databases Depressed mood Development Diagnosis Diagnostic Diagnostic and Statistical Manual Diagnostic and Statistical Manual of Mental Disorders Differential Diagnosis Dimensions Disease Disruptive Behavior Disorder Dysthymic Disorder Excision Feeling suicidal Frequencies Fright Future Generalized Anxiety Disorder Goals Health Health Occupations Health Professional Impairment Individual International Interview Investigation Knowledge Life Link Literature Major Depressive Disorder Manuals Measures Mental Depression Mental Health Mental disorders Methodology Modeling Modification Mood Disorders Moods National Institute of Mental Health Natural History Oppositional Defiant Disorder Outcome Panic Disorder Pattern Phobic anxiety disorder Prevalence Probability Samples Procedures Psychiatric Diagnosis Psychiatrist Psychologist Psychometrics Psychopathology Qualifier Research Research Personnel Resources Role Sampling Schedule Severities Social Functioning Source Specific qualifier value Structure Symptoms System Taxon Testing Time United States National Institutes of Health Variant Work Youth age related base care systems child well being comparative comparison group cost depressive symptoms disease classification disorder subtype early onset experience follow-up improved instrument longitudinal course meetings minor depressive disorder named group novel strategies outcome forecast prospective response stressor symposium young adult

项目摘要

DESCRIPTION (provided by applicant): Since the development of DSM-III in 1980, and through its subsequent revisions (DSM-III-R, DSM-IV), DSM criteria have become almost universally accepted as a basis for diagnosis in the mental health professions. Despite this broad acceptance, there is a paucity of empirical data available that support the highly specified diagnostic formations embodied in manual. The impact that adding, removing, or otherwise altering criteria may have on disorder prevalence, natural history, or associated impairment has not been well studied. There is little consensus on the issue of comorbidity and the extent to which this phenomenon represents misplaced diagnostic boundaries, responses to common antecedents, or causal linkages between disorders. Finally, and especially important to child psychiatry, there is relatively little information available about developmental differences in the expression and significance of DSM-defined disorders. The proposed project would compile and analyze a database of diagnostic and symptom data collected by 16 investigations of youth, all of which used a DSM- linked version of the DISC. The total database would have data on approximately 19,000 children and adolescents -- longitudinal data is available on approximately 14,000 of these. The specific analytic aims outlined in the proposal (examining the validity of diagnostic subtypes and specifiers; understanding diagnostic boundaries and comorbidity; justifying diagnostic thresholds; studying the appropriateness of individual symptom criteria; comparing dimensional and categorical definitions) address the most important and pressing diagnostic and classification issues facing the field and will inform the epistemological underpinnings of child and adolescent psychiatric nosology. In a cost-efficient, manner this project will afford a unique opportunity to address many questions that can only be answered with such a large aggregated dataset with well-defined samples assessed with a standardized, comprehensive and transparent methodology. The aggregated data will also represent an invaluable data resource for future research. PUBLIC HEALTH RELEVANCE: The DSM has become the established standard for psychiatric diagnosis but many of the categories and criteria specified in the manual have not been based upon or tested with empirical data. The proposed project will compile and analyze a database of diagnostic and symptom data on approximately 19,000 children and adolescents to address the validity of current and proposed diagnostic categories and criteria. The project will also provide an invaluable data resource for addressing research questions that require large samples assessed with a standardized, comprehensive and transparent methodology.

描述（由申请人提供）：自1980年DSM-III开发以来，通过其随后的修订（DSM-III-R，DSM-IV），DSM标准几乎已被普遍接受为精神卫生职业中诊断的基础。尽管接受了这种广泛的认可，但可用的经验数据很少支持手动体现的高度指定的诊断形成。尚未对疾病患病率，自然史或相关障碍产生的添加，删除或更改标准的影响尚未得到很好的研究。关于合并症的问题几乎没有共识，以及这种现象代表放错了位置的诊断边界，对共同先例的反应或疾病之间的因果关系。最后，对于儿童精神病学尤其重要，关于DSM定义疾病的表达和意义的发育差异的信息相对较少。拟议的项目将通过16个对青年的调查收集的诊断和症状数据数据库进行编译和分析，所有这些数据都使用了DSM链接版本的光盘。总数据库将拥有大约19,000名儿童和青少年的数据 - 大约14,000个纵向数据可用。提案中概述的具体分析目的（检查诊断性亚型和指定者的有效性；了解诊断界限和合并症；证明诊断性阈值合理；研究个人症状标准的适当性；比较最重要的和分类的范围，并将面对诊断的阶段和范围的阶段和范围的阶段介绍，并将范围识别为问题，并在诊断的问题上进行识别，并确定问题的问题，并确定了问题的问题，并确定了问题的问题，并确定了问题的问题，并确定了问题的问题，并确定了问题的问题，并确定了问题的问题，并确定了问题的问题，并确定了问题的范围，并且会遇到问题的范围，并确定范围的问题，并将其确定为问题。青春期精神病学。以经济高效的方式，该项目将提供一个独特的机会来解决许多问题，只有这样一个大型的汇总数据集，并使用标准化，全面且透明的方法评估了明确定义的样本。汇总数据还将代表未来研究的宝贵数据资源。公共卫生相关性：DSM已成为精神病诊断的既定标准，但是手册中指定的许多类别和标准尚未基于或测试经验数据。拟议的项目将对大约19,000名儿童和青少年的诊断和症状数据进行编译和分析，以解决当前和拟议的诊断类别和标准的有效性。该项目还将提供宝贵的数据资源，以解决需要使用标准化，全面和透明方法评估的大量样本的研究问题。