Immunological therapies for cancer and autoimmunity

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The programme team comprises a group of leading scientists with a history of successful investigation into the mechanisms and treatment of diseases in which the immune system plays a role in their development. These include cancers of the cervix and blood system, and autoimmune diseases such as rheumatoid arthritis and type 1 diabetes. Working together, the team have made discoveries that have led to testing and clinical development of new treatments for these diseases. In this programme, the team aims to discover mechanisms regulating the immune response, and to exploit this knowledge to define new ways of switching on or off, specific immune responses. We will particularly seek to develop novel vaccines for chronic infections and autoimmune diseases, and to improve the safety of bone marrow transplantation.