Immunological therapies for cancer and autoimmunity

癌症和自身免疫的免疫疗法

• 批准号: nhmrc : 351439
• 负责人: Prof Geoff Hill
• 金额: $ 328.62万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Programs
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/immunological-therapies-cancer-autoimmunity/101173
• 关键词: Immunological; therapies; cancer; autoimmunity

The programme team comprises a group of leading scientists with a history of successful investigation into the mechanisms and treatment of diseases in which the immune system plays a role in their development. These include cancers of the cervix and blood system, and autoimmune diseases such as rheumatoid arthritis and type 1 diabetes. Working together, the team have made discoveries that have led to testing and clinical development of new treatments for these diseases. In this programme, the team aims to discover mechanisms regulating the immune response, and to exploit this knowledge to define new ways of switching on or off, specific immune responses. We will particularly seek to develop novel vaccines for chronic infections and autoimmune diseases, and to improve the safety of bone marrow transplantation.

该方案小组由一群顶尖的科学家组成，他们在免疫系统在疾病发展中发挥作用的疾病的机制和治疗方面有成功研究的历史。这些疾病包括宫颈癌和血液系统癌，以及风湿性关节炎和1型糖尿病等自身免疫性疾病。通过共同努力，该团队取得了一些发现，这些发现导致了这些疾病的新疗法的测试和临床开发。在这个项目中，该团队的目标是发现调节免疫反应的机制，并利用这一知识来定义开启或关闭特定免疫反应的新方法。我们将特别寻求开发针对慢性感染和自身免疫性疾病的新型疫苗，并提高骨髓移植的安全性。