Imroving transplantation outcomes

改善移植结果

• 批准号: nhmrc : 1107797
• 负责人: Prof Geoff Hill
• 金额: $ 63.74万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/imroving-transplantation-outcomes/663001
• 关键词: Imroving; transplantation; outcomes

The transplantation of healthy stem cells from a donor into a recipient with blood cancer (stem cell transplantation) is the most effective curative therapy for the majority of patients. Unfortunately this process results in unwanted, often fatal, side effects including infection, a rejection process known as graft-versus-host disease and in some patients, the leukaemia still recurs. This research will refine new treatments focused on overcoming these limitations and improving transplant outcome

将健康的干细胞从供体移植到患有血癌的受体（干细胞移植）是对大多数患者最有效的治疗方法。不幸的是，这一过程会导致不必要的，往往是致命的副作用，包括感染，一种被称为移植物抗宿主病的排斥过程，在一些患者中，白血病仍然复发。这项研究将改进新的治疗方法，重点是克服这些限制和改善移植结果