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中文摘要
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这一核心将监督整个中心的运作。贾维特博士,谁担任总中心PI,将 担任核心领导人。该核心的具体目标是:(1)提供行政监督, 支持所有Conte项目和核心,2)支持Conte相关委员会的运作,咨询 董事会和会议,以及3)协调夏季本科生研究计划。因此, 核心将管理指导委员会、内部和外部咨询委员会以及中心会议。 该Conte中心代表了研究人员之间的合作,专注于神经生理学基础, 精神分裂症,以及精神分裂症研究中心(SRC)目前项目的自然产物 在NKI/NYUSOM。参与该中心的所有研究者都与SRC建立了联系, 通过联合出版物、联合资助的项目或提交的研究申请证明。此外,所有 研究人员是各自领域的领导者,赠款、出版物和科学研究证明了这一点。 仙女该Conte将扩展和深化正在进行的合作,同时增加交叉施肥 "纵向"-基础科学家和临床科学家之间,"横向"-基础科学家和临床科学家之间 研究人员行政核心的总体目标是提供尽可能高水平的 支持参与的科学家,同时确保尽可能高水平的协同互动。 行政核心将作为中心的通信骨干, 行政专门知识,以尽量减少对调查员个人的行政负担,同时保持 最高标准的人类和动物受试者福利保护,以及贯穿始终的财务责任 中心。行政核心将监测项目相对于拟议指导方针的进展情况, 我将不断警惕的机会,采用新的技术和方法,以优化 现有的方法,并克服障碍,以成功的研究,无论何时何地发生。 夏季本科研究计划将建立在NYUSoM现有的计划,并将提供 有兴趣的本科生有机会参加夏季心理健康研究。的 SURP将为选定的本科生提供助学金,研究和旅行支持。将特别强调 招聘少数民族和弱势群体候选人。 相关性(参见说明): 精神分裂症是一种严重的精神障碍。神经认知功能障碍是 精神分裂症和长期预后不良的主要决定因素。这个核心是一个中心的一部分 应用于确定精神分裂症神经认知功能障碍的脑机制 特别强调感觉处理功能障碍。该核心将管理整体 中心,并将支持夏季本科生研究计划。
英文摘要
This core will oversee function of the Center as a whole. Dr. Javitt, who serves as overall Center PI, will serve as Core leader. The Specific aims of the Core are 1) to provide Administrative supervision and support to all Conte projects and cores, 2) to support operation of Conte-related committees, advisory boards and meetings, and 3) to coordinate the Summer Undergraduate Research Program. As such, the Core will administer the Steering Committee, Internal and External Advisory Boards, and Center meetings. This Conte Center represents a collaboration among investigators focused on neurophysiological basis of schizophrenia, and a natural outgrowth of current projects within the Schizophrenia Research Center (SRC) at NKI/NYUSOM. All investigators participating in this Center have established ties to the SRC, as evidenced by joint publications, jointly funded projects, or submitted research applications. Further, all investigators are leaders in their respective fields, as evidenced by grants, publications and scientific nnovation. This Conte will extend and deepen ongoing collaborations, while increasing cross-fertilization both "vertically" - between basic and clinical scientists - and "horizontally" - among both basic and clinical researchers. The overarching goal of the Administrative Core is to provide the highest possible level of support to the participating scientists, while insuring the highest possible levels of synergistic interaction. The Administrative Core will serve as the communication backbone for the Center as well as a repository of administrative expertise for minimizing administrative burden to individual investigators while maintaining the highest standards of human and animal subject welfare protection, and financial accountability throughout the Center. The Administrative Core will monitor progress of Projects relative to proposed guidelines, and will be constantly vigilant for opportunities to incorporate novel techniques and methodologies, to optimize existing approaches, and to overcome hurdles to successful research whenever and wherever they occur. The Summer Undergraduate Research Program will build from existing programs at NYUSoM and will offer an opportunity for interested undergraduate students to participate in summer mental health research. The SURP will provide stipends, research and travel support for selected undergraduates. Special emphasis will be placed on recruitment of minority and disadvantaged candidates. RELEVANCE (See instructions): Schizophrenia is a major mental disorder. Neurocognitive dysfunction is a core component of schizophrenia and a major determinant of poor long-term outcome. This Core is part of a Center application to determine brain mechanisms underlying neurocognitive dysfunction in schizophrenia with particular emphasis on sensory processing dysfunction. This Core will administer the overall Center and will support the Summer Undergraduate Research Program.
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Auditory event-related potentials as in vivo preclinical assays of circuit engagement for E/I-based therapeutic development
Neural Mechanisms of Reading Dysfunction in Schizophrenia
Neural Mechanisms of Reading Dysfunction in Schizophrenia
Neural Mechanisms of Reading Dysfunction in Schizophrenia
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