Cell and Molecular Biology of Reproduction

描述（由申请人提供）：该培训计划主要位于伍斯特的马萨诸塞州医学院（UMMS），并在阿默斯特的马萨诸塞州大学（UMass Amherst）提供细胞和生殖分子生物学的博士后培训。每年将支持3名博士后学员;每个学员通常在没有相关博士后经验的情况下进入该计划，并支持两年，并有可能支持第三年。该计划是跨学科的，并借鉴了来自UMMS的生物化学和分子药理学，细胞生物学，分子医学，儿科学和生理学系以及UMass Amherst的兽医和动物科学系的教师。18名培训教师都是在生殖生物学的一个或多个领域进行研究的杰出科学家。UMMS和UMass Amherst拥有最先进的研究设施，并为博士后培训提供一流的环境。培训的目标有两个方面：1）培养年轻科学家识别和定义问题的能力，这些问题将阐明生殖生物学中的基本问题; 2）提供必要的环境和指导，以获得必要的背景，知识严谨性以及回答这些问题的分析和技术技能。受训人员还接受道德和负责任的研究行为方面的指导。受训人员在本计划的支持下不承担教学职责。培训结束后，学员应做好充分准备，在学术界或工业界开展生殖生物学方面的独立研究。 公共卫生相关性：该计划将有助于满足国家对高技能年轻研究人员的需求，他们可以带来最先进的细胞和分子生物学方法来解决生殖生物学中的重要问题。培训结束后，受训人员将准备在避孕、不孕症以及影响发育和生殖系统的遗传和后天疾病等领域进行独立研究。科学家也将接受培训，以帮助实现人类胚胎干细胞用于细胞治疗的巨大前景。

DESCRIPTION (provided by applicant): This training program, which is located primarily at the University of Massachusetts Medical School (UMMS) in Worcester with additional mentors at the University of Massachusetts in Amherst (UMass Amherst), provides postdoctoral training in the cell and molecular biology of reproduction. A total of 3 postdoctoral trainees will be supported each year; each trainee generally enters the program with no relevant postdoctoral experience and is supported for two years, with the possibility of a third year of support. The program is interdisciplinary and draws upon faculty from the Departments of Biochemistry and Molecular Pharmacology, Cell Biology, Molecular Medicine, Pediatrics, and Physiology at UMMS and the Department of Veterinary and Animal Sciences at UMass Amherst. The 18 training faculty members are all outstanding scientists carrying out research in one or more areas of reproductive biology. UMMS and UMass Amherst have state-of-the-art research facilities and provide superb environments for postdoctoral training. The goal of the training is two-fold: 1) to develop in young scientists the ability to recognize and define questions that will illuminate fundamental issues in reproductive biology; and 2) to provide the environment and guidance needed to attain the necessary background, intellectual rigor, and analytical and technical skills to answer these questions. Trainees also are instructed in ethics and responsible conduct of research. Trainees do not have teaching duties while supported by this program. Upon completion of training, trainees should be well prepared to carry out independent research in reproductive biology in academia or industry. PUBLIC HEALTH RELEVANCE: The program will help meet the national need for highly skilled young investigators who can bring state-of-the-art cell and molecular biological approaches to bear on important problems in reproductive biology. Upon completion of training, trainees will be prepared to carry out independent research in areas relevant to contraception, infertility, and inherited and acquired diseases that affect development and the reproductive system. Scientists also will be trained to help realize the great promise of human embryonic stem cells for cell-based therapies.