Electric field effects on cochlear tissues

电场对耳蜗组织的影响

• 批准号: LP140101008
• 负责人: Prof Gary Housley
• 金额: $ 24.67万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-06-30 至 2018-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP140101008
• 关键词: Electric; field; effects; cochlear; tissues

The project aims to solve the underlying biology of how electricity flows through the cochlear tissues, where and how electrical stimulation excites the auditory neurons, and what the effects of sustained electrical stimulation are on the nerve fibre growth and function. The research aims to show how electric fields can be controlled in the cochlea, and how auditory nerve fibres are affected at the cellular and molecular level. The long-term aim is to utilise these findings to improve the control of neuronal excitability, for development of interfaces with the nervous system.

该项目旨在解决电流如何流经耳蜗组织的潜在生物学问题，电刺激在何处以及如何刺激听觉神经元，以及持续电刺激对神经纤维生长和功能的影响。这项研究旨在展示电场是如何在耳蜗中被控制的，以及听神经纤维是如何在细胞和分子水平上受到影响的。长期目标是利用这些发现来改善对神经元兴奋性的控制，以开发与神经系统的接口。