The Southwest National Primate Research Center

西南国家灵长类动物研究中心

• 批准号: 8119190
• 负责人: Kenneth Parkhurst Trevett
• 金额: $ 50万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-06 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8119190
• 关键词: Aging; Biomedical Research; Breeding; Callithrix; Callithrix jacchus jacchus; Chronic Disease; Commit; Communicable Diseases; Communities; Development; Disease; Focus Groups; Foundations; Genetic Research; Genomics; Genotype; Grant; Health; Institution; Macaca; Macaca mulatta; Mission; Neonatal; Pan Genus; Papio; Pharmaceutical Preparations; Population; Primates; Research; Research Infrastructure; Research Personnel; Resources; Services; Translational Research; base; biodefense; gene discovery; genetic resource; improved; innovation; meetings; nonhuman primate; programs; research facility; stem cell biology; vaccine development

DESCRIPTION (provided by applicant): The objective of this proposal is to continue support of the infrastructure of the Southwest National Primate Research Center (SNPRC). The SNPRC is located on the campus of the Southwest Foundation for Biomedical Research, its host institution. The SNPRC maintains over 4,000 nonhuman primates, primarily baboons, macaques, marmosets, and chimpanzees. It maintains large breeding populations of baboons, rhesus macaques, and common marmosets. During the current grant period, the SNPRC provided resources to 290 investigators from 35 states. The base grant is composed of four types of components: Administration, Primate Resources, Veterinary Resources, and Research Resources. The Research Resource components and the research programs that utilize them are divided among four Focus Groups: Infectious Diseases and Biodefense, Chronic Diseases, Development and Aging, and Genomics. The mission of the SNPRC is "To improve the health of our global community through innovative biomedical research with nonhuman primates." Consistent with this mission, the SNPRC is committed to translational research and is a partner in two CTSA applications that are in review. The administration, primate resource, veterinary resource, and research resource infrastructures supported by the base grant enable the SNPRC to be responsive to national biomedical research needs and to accommodate investigators who want to access Center resources for collaborative research purposes. Special, and in some cases unique, strengths of the SNPRC are a wide variety of primate species to meet diverse research needs; the largest pedigreed and genotyped population of nonhuman primates available for genetic research; broad research opportunities with the largest chimpanzee population at any National Primate Research Center; ABSL-3 and ABSL-4 facilities; research emphasis and expertise on gene discovery for common chronic diseases, development of vaccines and drugs for infectious diseases, preventions and treatments of neonatal diseases, and stem cell biology; and service as a national resource for genetic management of nonhuman primates.

描述(申请人提供)：本提案的目的是继续支持西南国家灵长类动物研究中心(SNPRC)的基础设施。SNPRC位于其主办机构西南生物医学研究基金会的校园内。SNPRC饲养着4000多种非人类灵长类动物，主要是狒狒、猕猴、绒猴和黑猩猩。它维持着大量的狒狒、恒河猴和普通恒河猴的繁殖种群。在目前的赠款期间，SNPRC向来自35个州的290名调查人员提供了资源。基本补助金由四种类型的组成部分组成：行政、灵长类资源、兽医资源和研究资源。研究资源组成和利用它们的研究计划分为四个焦点组：传染病和生物防御、慢性病、发育和老龄化以及基因组学。 SNPRC的使命是“通过对非人类灵长类动物的创新生物医学研究，改善我们全球社区的健康。”本着这一使命，SNPRC致力于翻译研究，并是正在审查的两个CTSA应用程序的合作伙伴。由基础拨款支持的行政、灵长类资源、兽医资源和研究资源基础设施使SNPRC能够响应国家生物医学研究需求，并容纳希望访问中心资源用于合作研究目的的研究人员。SNPRC的特殊但在某些情况下是独特的优势是：种类繁多的灵长类动物，以满足多样化的研究需求；可用于遗传研究的最大的非人灵长类动物谱系和基因分型种群；在任何国家灵长类动物研究中心中拥有最大黑猩猩种群的广泛研究机会；ABSL-3和ABSL-4设施；常见慢性病基因发现的研究重点和专业知识；传染病疫苗和药物的开发；新生儿疾病的预防和治疗以及干细胞生物学；作为国家非人灵长类动物遗传管理资源提供服务。