The Southwest National Primate Research Center

西南国家灵长类动物研究中心

• 批准号: 8306168
• 负责人: Kenneth Parkhurst Trevett
• 金额: $ 742.08万
• 依托单位: TEXAS BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-06 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8306168
• 关键词: Aging; Biomedical Research; Breeding; Callithrix; Callithrix jacchus jacchus; Chronic Disease; Commit; Communicable Diseases; Communities; Development; Disease; Focus Groups; Foundations; Genetic Research; Genomics; Genotype; Grant; Health; Institution; Macaca; Macaca mulatta; Mission; Neonatal; Pan Genus; Papio; Pharmaceutical Preparations; Population; Primates; Research; Research Infrastructure; Research Personnel; Resources; Services; Translational Research; base; biodefense; disorder prevention; gene discovery; genetic resource; improved; innovation; meetings; nonhuman primate; programs; stem cell biology; vaccine development

The objective of this proposal is to continue support of the infrastructure of the Southwest National Primate Research Center (SNPRC). The SNPRC is located on the campus of the Southwest Foundation for Biomedical Research, its host institution. The SNPRC maintains over 4,000 nonhuman primates, primarily baboons, macaques, marmosets, and chimpanzees. It maintains large breeding populations of baboons, rhesus macaques, and common marmosets. During the current grant period, the SNPRC provided resources to 290 investigators from 35 states. The base grant is composed of four types of components: Administration, Primate Resources, Veterinary Resources, and Research Resources. The Research Resource components and the research programs that utilize them are divided among four Focus Groups: Infectious Diseases and Biodefense, Chronic Diseases, Development and Aging, and Genomics. The mission of the SNPRC is "To improve the health of our global community through innovative biomedical research with nonhuman primates." Consistent with this mission, the SNPRC is committed to translational research and is a partner in two CTSA applications that are in review. The administration, primate resource, veterinary resource, and research resource infrastructures supported by the base grant enable the SNPRC to be responsive to national biomedical research needs and to accommodate investigators who want to access Center resources for collaborative research purposes. Special, and in some cases unique, strengths of the SNPRC are a wide variety of primate species to meet diverse research needs; the largest pedigreed and genotyped population of nonhuman primates available for genetic research; broad research opportunities with the largest chimpanzee population at any National Primate Research Center; ABSL-3 and ABSL-4 facilities; research emphasis and expertise on gene discovery for common chronic diseases, development of vaccines and drugs for infectious diseases, preventions and treatments of neonatal diseases, and stem cell biology; and service as a national resource for genetic management of nonhuman primates.

该提案的目的是继续支持西南国家大学的基础设施建设 灵长类动物研究中心（SNPRC）。 SNPRC 位于西南基金会校园内 生物医学研究中心，其主办机构。 SNPRC 饲养着超过 4,000 只非人类灵长类动物，主要是 狒狒、猕猴、狨猴和黑猩猩。它维持着大量的狒狒繁殖种群， 恒河猴和普通狨猴。在当前拨款期内，SNPRC 提供了 向来自 35 个州的 290 名调查人员提供资源。基本补助金由四种类型组成： 管理、灵长类资源、兽医资源和研究资源。研究 资源组成部分和利用它们的研究项目分为四个焦点小组： 传染病和生物防御、慢性病、发育和衰老以及基因组学。 SNPRC 的使命是“通过创新改善全球社区的健康” 非人类灵长类动物的生物医学研究。”与这一使命相一致，SNPRC 致力于 转化研究，并且是两项正在审查的 CTSA 申请的合作伙伴。行政部门， 由基本拨款支持的灵长类资源、兽医资源和研究资源基础设施 使 SNPRC 能够响应国家生物医学研究需求并适应 想要访问中心资源以进行协作研究目的的研究人员。特别的，并且在 在某些情况下是独特的，SNPRC 的优势是灵长类动物种类繁多，可以满足多样化的研究 需要；可用于遗传研究的最大系谱和基因分型的非人类灵长类动物群体 研究;与所有国家灵长类动物中数量最多的黑猩猩进行广泛的研究机会 研究中心； ABSL-3 和 ABSL-4 设施；基因发现的研究重点和专业知识 常见慢性病、传染病疫苗和药物的研制、预防和 新生儿疾病治疗和干细胞生物学；和作为国家遗传资源的服务 非人类灵长类动物的管理。