Training in Translational Science and Cardiovascular Medicine

转化科学和心血管医学培训

• 批准号: 8130996
• 负责人: Kent L.R. Thornburg
• 金额: $ 39.53万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8130996
• 关键词: Cardiovascular system; Medicine; Training; Translational Research

DESCRIPTION (provided by applicant): This revised proposal seeks funds for a new training program in translational research applied to cardiovascular disease. The program will recruit PhD and MD trainees through the Division of Cardiovascular Medicine at the Oregon Health & Science University and the Heart Research Center. Six post-doctoral fellows will be offered funding for two years of research training. The program will offer exciting opportunities for bench to bedside training in one of five established groups that specialize in 1) the early origins of adult disease, 2) obesity/diabetes, 3) cell signaling, 4) physiological systems, and 5) human research. The 34 faculty are highly recognized and funded scientists who have a track record of training postdoctoral fellows. Specialty training will include molecular imaging, mouse genetic models, primate models of obesity and cardiovascular disease, clinical MRI research, mechanical forces-gene expression links, mathematical models of cardiovascular dysregulation. Laboratory research will be supplemented by course work, seminars, journal club, and meetings within a specific science group. This program is unique at OHSU in that mentoring will be carried out in a team approach. A basic scientist and a clinical scientist plus one additional scientist will serve on each trainee's mentoring committee. The training outcome will be scientists with a broad outlook and a focus on bringing science to the benefit of patients. The application includes a strong recruitment program for underserved minority trainees and an evaluation process. A strong Program Advisory Committee will monitor the progress of every trainee as they meet specific mileposts in preparation for a research career. These scientists that graduate from this program will be prepared to investigate major public health issues including the increasing global burden of stroke, diabetes, coronary heart disease, heart failure and obesity.

描述(由申请者提供)：这项修订后的提案寻求为应用于心血管疾病的转化研究的新培训计划提供资金。该计划将通过俄勒冈健康与科学大学心血管医学部和心脏研究中心招聘博士生和医学博士实习生。六名博士后研究员将获得为期两年的研究培训资金。该计划将为板凳到床边培训提供令人兴奋的机会，在五个成熟的小组之一，这五个小组专门从事1)成人疾病的早期起源，2)肥胖/糖尿病，3)细胞信号，4)生理系统，和5)人类研究。这34名教师是高度认可和资助的科学家，他们有培训博士后研究员的记录。专业培训将包括分子成像、小鼠遗传模型、肥胖和心血管疾病的灵长类动物模型、临床核磁共振研究、机械力-基因表达链接、心血管失调的数学模型。实验室研究将通过课程作业、研讨会、期刊俱乐部和特定科学小组内的会议来补充。这个项目在OHSU是独一无二的，因为指导将以团队的方式进行。每个学员的指导委员会将有一名基础科学家和一名临床科学家，外加一名额外的科学家。培训的结果将是具有广阔前景并专注于将科学造福于患者的科学家。该申请包括一个针对服务不足的少数族裔受训人员的强有力的招聘计划和一个评估程序。一个强大的计划咨询委员会将监督每个受训人员的进展情况，因为他们在为研究生涯做准备的过程中达到了特定的里程碑。这些从该项目毕业的科学家将准备调查主要的公共卫生问题，包括日益增加的全球中风、糖尿病、冠心病、心力衰竭和肥胖症的负担。