CH/BIDMC/Harvard Medical School Neurology Resident Research Education Program

CH/BIDMC/哈佛大学医学院神经病学住院医师研究教育计划

• 批准号: 8066288
• 负责人: ALBERT Mark GALABURDA
• 金额: --
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8066288
• 关键词: Adult; Affect; Anesthesia procedures; Area; Award; Boston; Clinical; Data; Early Diagnosis; Education; Effectiveness; Environment; Faculty; Fellowship; Funding; Future; Israel; Laboratories; Learning; Medical Research; Medical center; Mentors; Methodology; Molecular; Monitor; Nervous system structure; Neurobiology; Neurology; Neurosciences; Neurosciences Research; Pain Research; Participant; Pediatric Hospitals; Pediatric Neurology; Physicians; Publications; Recording of previous events; Recruitment Activity; Research; Research Personnel; Residencies; Scientist; Training; Training Programs; Translational Research; United States National Institutes of Health; Work; design; experience; medical schools; neuropathology; neurosurgery; programs; public health relevance; responsible research conduct; skills; translational neuroscience

DESCRIPTION (provided by applicant): The aim of this award is to create an opportunity for selected residents in the neurology residency training programs of the Beth Israel Deaconess Medical Center (BIDMC) and the Children's Hospital Boston (CHB) to participate for 9 to 24 months in an intensive, mentored, research educational experience during the third year of residency and subsequent fellowship years. This training will be designed to prepare participating residents for successful competition for independent mentored research awards, and will facilitate the transition from resident/fellow to clinician-scientist. Each participant will work with one of 37 mentors, who have been recruited from the faculties of CHB, BIDMC, and Harvard Medical School (HMS). All have active NIH funding and a history of training clinician-scientists. The proposed mentors cover all major areas of the clinical and basic neurosciences, and include 20 investigators from CHB, 16 investigators from BIDMC, and one investigator from HMS (Dr. Michael Greenberg, former leader of the Neurobiology Program at CHB, now Chair of Neurobiology at HMS). Seventeen of these investigators are engaged in clinical/translational neuroscience research, twelve conduct basic neuroscience research, and eight are involved in both basic and clinical/translational research. Mentors have been drawn not only from the Departments of Neurology/Neurobiology, but also from the CHB Division of Neuropathology, the CHB Division of Neuroradiology, the CHB Department of Neurosurgery, the BIDMC Division of Neuropathology, and the Pain Research Program of the BIDMC Department of Anesthesia. Selected resident participants will learn state-of- the-art laboratory skills and will acquire the critical expertise necessary for the conduct of responsible research. Data collected and analyzed will serve for publications as well as for future NIH proposals. The program will be governed by a Steering Committee consisting of the PD/PIs, the Department Chairs, and the Residency Directors of the participating residency programs. This Committee will work together to recruit and select trainees, to monitor their progress, and to evaluate the effectiveness of the training experience. PUBLIC HEALTH RELEVANCE: Illnesses affecting the nervous system remain a great challenge to medical research. The discovery of the causes of these illnesses, leading to earlier diagnosis and better treatments, requires research that relies increasingly on conceptual complexities and sophisticated methodologies. The present R25 proposal is aimed at developing researchers that can combine the clinical expertise obtained during residency with a well developed and focused investigative research program. Neurology residents are keenly aware of the problems that need to be solved and are especially motivated and energized to solve them. The CHB/BIDMC residency program combines both adult and child neurology within an environment that has great depth in basic and clinical neuroscience. Mentors chosen for the R25 include leading NIH funded basic cellular and molecular neuroscientists, as well as successful physician scientists actively engaged in clinical and basic neuroscience and experienced in, and eager to train physician scientists. The main focus of the proposed program will be to prepare physicians for independent and competitive research.

描述（由申请人提供）：该奖项的目的是为贝斯以色列女执事医疗中心 (BIDMC) 和波士顿儿童医院 (CHB) 的神经病学住院医师培训项目的选定住院医师创造机会，让他们在住院医师的第三年和随后的进修期间参加为期 9 至 24 个月的强化、指导性研究教育经历。该培训旨在帮助参与的住院医师为成功竞争独立指导的研究奖项做好准备，并将促进从住院医师/研究员向临床医生科学家的过渡。每位参与者将与 37 名导师中的一位一起工作，这些导师是从 CHB、BIDMC 和哈佛医学院 (HMS) 的院系中招募的。所有这些都拥有美国国立卫生研究院 (NIH) 的积极资助和培训临床医生科学家的历史。拟议的导师涵盖了临床和基础神经科学的所有主要领域，包括 20 名来自 CHB 的研究人员、16 名来自 BIDMC 的研究人员和 1 名来自 HMS 的研究人员（Michael Greenberg 博士，CHB 神经生物学项目前负责人，现任 HMS 神经生物学主席）。其中 17 名研究人员从事临床/转化神经科学研究，12 名研究人员进行基础神经科学研究，8 名研究人员同时参与基础研究和临床/转化研究。导师不仅来自神经病学/神经生物学系，还来自 CHB 神经病理学部、CHB 神经放射学部、CHB 神经外科、BIDMC 神经病理学部以及 BIDMC 麻醉部疼痛研究项目。选定的常驻参与者将学习最先进的实验室技能，并将获得进行负责任的研究所需的关键专业知识。收集和分析的数据将用于出版物以及国家卫生研究院未来的提案。该计划将由指导委员会管理，该委员会由参与住院医师计划的 PD/PI、系主任和住院医师主任组成。该委员会将共同招募和选拔受训人员，监督他们的进展，并评估培训经验的有效性。 公共卫生相关性：影响神经系统的疾病仍然是医学研究的巨大挑战。发现这些疾病的原因，从而实现更早的诊断和更好的治疗，需要越来越依赖概念复杂性和复杂方法的研究。目前的 R25 提案旨在培养研究人员，将住院期间获得的临床专业知识与完善且重点突出的调查研究计划相结合。神经内科住院医生敏锐地意识到需要解决的问题，并且特别有动力和精力去解决这些问题。 CHB/BIDMC 住院医师计划将成人和儿童神经病学结合在一个对基础和临床神经科学有深入了解的环境中。 R25 选定的导师包括 NIH 资助的领先基础细胞和分子神经科学家，以及积极从事临床和基础神经科学、经验丰富且渴望培训医师科学家的成功医师科学家。拟议项目的主要重点是让医生为独立和竞争性研究做好准备。