Training in Cellular and Molecular Imaging of Cancer

癌症细胞和分子成像培训

• 批准号: 8105196
• 负责人: John C Gore
• 金额: $ 52.7万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-10 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8105196
• 关键词: Address; Applications Grants; Biological; Biological Process; Biological Sciences; Biology; Biomedical Engineering; Biomedical Research; Biophysics; Cancer Biology; Cancer Center; Chemistry; Competence; Diagnosis; Discipline; Doctor of Philosophy; Educational Curriculum; Educational workshop; Electrical Engineering; Ensure; Ethics; Funding; Goals; Grant; Health; Human Resources; Image; Imaging Techniques; Institutes; Investigation; Journals; Laboratories; Malignant Neoplasms; Mentors; Molecular; Patient Care; Physics; Plant Roots; Publications; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Roentgen Rays; Science; Scientist; Stress; Structure; Students; Techniques; Training; Training Programs; United States National Institutes of Health; Universities; Work; Writing; anticancer research; bioimaging; cancer imaging; cellular imaging; design; experience; in vivo; insight; knowledge base; medical schools; molecular/cellular imaging; multidisciplinary; physical science; pre-doctoral; programs; skills; tool

DESCRIPTION (provided by applicant): This application seeks support for a new, pre-doctoral educational and training program in Cellular and Molecular Imaging of Cancer at Vanderbilt University and Meharry Medical College. Biomedical imaging in vivo has developed from early uses of X-rays for diagnosis into a compendium of powerful techniques useful not only for patient care but also for the study of fundamental biological processes at the cellular and molecular levels. A variety of technical and molecular tools have evolved in recent years to propel cellular and molecular imaging into the forefront of cancer research. However, there is a critical need for scientists working at the interface of the physical and biological sciences to be trained in the ability to make the connections between imaging and basic biological processes in cancer. We propose to address this need with a comprehensive didactic educational and research training program designed for 10 outstanding pre-doctoral scientists (5 in each of two years). We will recruit trainees who have recently completed an undergraduate degree in a relevant science (particularly in Biomedical Engineering, Physics, Chemistry, Molecular Biophysics, Electrical Engineering or Biology) who will pursue research focused on molecular and/or cellular imaging of cancer. The didactic component of the proposed program will consist of courses, seminars, and a journal club. The courses will be organized into two tracks: one for those whose prior training emphasized relevant physical sciences and one for those with prior training in relevant biological sciences. The two tracks converge by the end of the second year so that all trainees, regardless of previous training, will be equipped with the necessary background to combine quantitative imaging and cancer biology at the highest levels. All trainees will be mentored in the ethics of biomedical research as well as in grant writing. Furthermore, both the didactic and research training components are designed to synthesize the physical and biological disciplines thereby creating a unique multi- and interdisciplinary training program for the study of cancer. For the research component, each trainee will have two mentors representing the disciplines of imaging science and cancer biology. Trainees will be integrated into ongoing NIH funded investigations within a leading biomedical imaging institute with strong connections and roots within a leading cancer center. By combining the resources and programs of the Vanderbilt University Institute of Imaging Science (VUIIS), the Vanderbilt-Ingram Cancer Center (VICC), and the Cancer Center at Meharry Medical College (CCM), we believe we have an outstanding infrastructure and personnel to create a leading, exemplary training program in cancer imaging.

描述（由申请人提供）：本申请寻求对范德比尔特大学和梅哈里医学院的癌症细胞和分子成像新的博士前教育和培训项目的支持。体内生物医学成像已从早期使用 X 射线进行诊断发展成为一系列强大的技术，不仅可用于患者护理，还可用于细胞和分子水平的基本生物过程的研究。近年来，各种技术和分子工具的发展推动细胞和分子成像进入癌症研究的前沿。然而，从事物理和生物科学交叉领域工作的科学家迫切需要接受培训，以掌握在癌症的成像和基本生物过程之间建立联系的能力。我们建议通过为 10 名优秀博士前科学家（每两年 5 名）设计的综合教学教育和研究培训计划来满足这一需求。我们将招募最近完成相关科学（特别是生物医学工程、物理、化学、分子生物物理学、电气工程或生物学）本科学位的学员，他们将从事癌症分子和/或细胞成像的研究。拟议项目的教学部分将包括课程、研讨会和期刊俱乐部。这些课程将分为两个轨道：一是针对那些之前接受过相关物理科学培训的人，另一是针对那些接受过相关生物科学培训的人。这两个方向在第二年年底汇合，以便所有学员，无论之前接受过何种培训，都将具备必要的背景，以最高水平将定量成像和癌症生物学结合起来。所有学员都将接受生物医学研究伦理以及资助写作方面的指导。此外，教学和研究培训部分旨在综合物理和生物学科，从而为癌症研究创建独特的多学科和跨学科培训计划。对于研究部分，每位学员将有两名代表成像科学和癌症生物学学科的导师。学员将参与美国国立卫生研究院 (NIH) 资助的领先生物医学成像研究所正在进行的研究，该研究所与领先的癌症中心有着密切的联系和根基。通过结合范德比尔特大学影像科学研究所 (VUIIS)、范德比尔特-英格拉姆癌症中心 (VICC) 和梅哈里医学院癌症中心 (CCM) 的资源和项目，我们相信我们拥有出色的基础设施和人员来创建领先的、堪称典范的癌症成像培训项目。