A Kenya Free of AIDS: Harnessing interdisciplinary science for HIV prevention

描述(由申请者提供)：我们建议华盛顿大学(UW)和内罗毕大学(UN)建立合作伙伴关系，努力建设一个没有艾滋病的肯尼亚。这一伙伴关系借鉴了威斯康星大学在联合国艾滋病毒/艾滋病研究能力建设方面20年的历史，以及人口科学界在内罗毕地区两个机构和其他机构的力量。该计划将支持华盛顿大学和内罗毕大学科学家之间正在进行的几项研究合作，这些合作处于有利地位，可以从社会科学的贡献中受益。这些项目中的每个都侧重于艾滋病毒预防。我们的具体目标是：1.通过综合(A)研究基础设施支助、(B)学院发展、(C)建立跨学科学术社区的机制和(D)加强内罗毕大学的IRB培训和程序，建设关于艾滋病毒/艾滋病的严格的社会和行为科学研究的能力；2.开展艾滋病毒预防的跨学科基础研究项目，重点是(A)寡妇遗传干预，(B)预防母婴传播(母婴传播)干预，(C)二级传播预防干预的翻译，以及(D)女性性工作者及其男性服务对象的生命历程研究。华盛顿大学为这一伙伴关系带来了强大的机构资源，艾滋病研究中心(CFAR)拥有活跃的社会行为和预防研究核心，人口统计学和生态研究中心(CSDE)拥有一批对艾滋病毒感兴趣的人口科学家。内罗毕大学有一套平行的单位，有一个新的大学艾滋病毒预防和研究中心(UCHIVPR)和一个成熟的人口研究研究所(PSRI)。在这两个机构，这笔赠款将有助于建立机制，促进社会科学、公共卫生和生物医学研究之间的互动。内罗毕也是非洲人口健康研究中心和人口理事会的所在地。双方都同意在这一倡议上与我们合作。随着行为改变在预防方面开始取得进展，新的生物医学预防干预措施正在上线。人们越来越认识到，生物医学和行为预防工作必须共同努力，才能使艾滋病毒预防和治疗工作取得成功。这一应用将提供一种机制，促进制定下一代艾滋病毒/艾滋病综合预防战略所需的跨学科研究。

DESCRIPTION (provided by applicant): We are proposing a partnership between the University of Washington (UW), and the University of Nairobi (UN) to work towards A Kenya Free of AIDS. This partnership draws on a 20 year history of the UW in building capacity for HIV/AIDS research at the UN, and the strength of the population science community at both institutions and in other institutions in the Nairobi area. The program will support several ongoing research collaborations between scientists at UW and the University of Nairobi that are well positioned to benefit from the contributions of social science. Each of these projects focuses on HIV prevention. Our specific aims are: 1. To build capacity for rigorous social and behavioral science research on HIV/AIDS through a combination of (a) Research infrastructure support, (b) Faculty development, (c) Mechanisms for building an interdisciplinary scholarly community, and (d) Enhancing IRB training and procedures at the University of Nairobi; and 2. To conduct foundational interdisciplinary research projects in HIV prevention focused on (a) A widow inheritance intervention, (b) A prevention of mother to child transmission (PMTCT) intervention, (c) Translation of a secondary transmission prevention intervention, and (d) A life course study of female sex workers and their male clients. The UW brings strong institutional resources to this partnership, with an active Sociobehavioral and Prevention Research core in the Center for AIDS Research (CFAR), and a group of population scientists with interests in HIV in the Center for Studies in Demography and Ecology (CSDE). The University of Nairobi has a parallel set of units, with a new University Centre for HIV Prevention and Research (UCHIVPR) and well established Population Studies Research Institute (PSRI). In both institutions, this grant will help to establish the mechanisms to promote the interaction between social science, public health and biomedical research. Nairobi is also home to the African Population Health Research Center, and the Population Council. Both have agreed to work together with us on this initiative. As behavior changes are beginning to make progress in prevention, new biomedical prevention interventions are coming online. Increasingly, it is recognized that the biomedical and behavioral prevention efforts must work together for HIV prevention and treatment efforts to succeed. This application will provide a mechanism to facilitate the cross-disciplinary research needed to develop the next generation of integrated HIV/AIDS prevention strategies.