A Kenya Free of AIDS: Harnessing interdisciplinary science for HIV prevention

描述（由申请人提供）：我们正在提议华盛顿大学（UW）和内罗毕大学（UN）之间的合作伙伴关系，共同努力实现一个无艾滋病的肯尼亚。这种伙伴关系利用了华盛顿大学在联合国开展艾滋病毒/艾滋病研究能力建设的20年历史，以及这两个机构和内罗毕地区其他机构的人口科学界的实力。该项目将支持华盛顿大学和内罗毕大学科学家之间正在进行的几项研究合作，这些合作将从社会科学的贡献中受益。每一个项目都侧重于艾滋病毒预防。我们的具体目标是：1。通过(a)研究基础设施支助、(b)教员发展、(c)建立跨学科学术共同体的机制和(d)加强内罗毕大学的伦理委员会培训和程序，建立关于艾滋病毒/艾滋病的严格的社会和行为科学研究的能力；和2。开展艾滋病毒预防的基础跨学科研究项目，重点是(a)寡妇遗传干预，(b)预防母婴传播（PMTCT）干预，(c)二次传播预防干预的翻译，以及(d)女性性工作者及其男性客户的生命历程研究。西澳大学为这一伙伴关系提供了强大的机构资源，艾滋病研究中心（CFAR）有一个活跃的社会行为和预防研究核心，人口与生态学研究中心（CSDE）有一群对艾滋病毒感兴趣的人口科学家。内罗毕大学有一组平行的单位，有一个新的大学艾滋病毒预防和研究中心（UCHIVPR）和一个建立良好的人口研究研究所（PSRI）。在这两个机构中，这笔赠款将有助于建立促进社会科学、公共卫生和生物医学研究之间相互作用的机制。内罗毕也是非洲人口健康研究中心和人口理事会的所在地。双方都同意就这一倡议与我们共同努力。随着行为改变开始在预防方面取得进展，新的生物医学预防干预措施正在上线。人们日益认识到，生物医学和行为预防工作必须共同努力，才能使艾滋病毒预防和治疗工作取得成功。这一应用将提供一种机制，促进制定下一代艾滋病毒/艾滋病综合预防战略所需的跨学科研究。

DESCRIPTION (provided by applicant): We are proposing a partnership between the University of Washington (UW), and the University of Nairobi (UN) to work towards A Kenya Free of AIDS. This partnership draws on a 20 year history of the UW in building capacity for HIV/AIDS research at the UN, and the strength of the population science community at both institutions and in other institutions in the Nairobi area. The program will support several ongoing research collaborations between scientists at UW and the University of Nairobi that are well positioned to benefit from the contributions of social science. Each of these projects focuses on HIV prevention. Our specific aims are: 1. To build capacity for rigorous social and behavioral science research on HIV/AIDS through a combination of (a) Research infrastructure support, (b) Faculty development, (c) Mechanisms for building an interdisciplinary scholarly community, and (d) Enhancing IRB training and procedures at the University of Nairobi; and 2. To conduct foundational interdisciplinary research projects in HIV prevention focused on (a) A widow inheritance intervention, (b) A prevention of mother to child transmission (PMTCT) intervention, (c) Translation of a secondary transmission prevention intervention, and (d) A life course study of female sex workers and their male clients. The UW brings strong institutional resources to this partnership, with an active Sociobehavioral and Prevention Research core in the Center for AIDS Research (CFAR), and a group of population scientists with interests in HIV in the Center for Studies in Demography and Ecology (CSDE). The University of Nairobi has a parallel set of units, with a new University Centre for HIV Prevention and Research (UCHIVPR) and well established Population Studies Research Institute (PSRI). In both institutions, this grant will help to establish the mechanisms to promote the interaction between social science, public health and biomedical research. Nairobi is also home to the African Population Health Research Center, and the Population Council. Both have agreed to work together with us on this initiative. As behavior changes are beginning to make progress in prevention, new biomedical prevention interventions are coming online. Increasingly, it is recognized that the biomedical and behavioral prevention efforts must work together for HIV prevention and treatment efforts to succeed. This application will provide a mechanism to facilitate the cross-disciplinary research needed to develop the next generation of integrated HIV/AIDS prevention strategies.