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Age-dependent immune responses to hepatitis B: a mouse model of human disease

Age-dependent immune responses to hepatitis B: a mouse model of human disease
对乙型肝炎的年龄依赖性免疫反应：人类疾病的小鼠模型
批准号：
8324407
负责人：
JODY L BARON
金额：
$38.63万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-09-06 至 2013-08-31
来源：
https://reporter.nih.gov/project-details/8324407
关键词：
Acute HepatitisAddressAdultAgeAnimal ModelB-LymphocytesBLR1 geneBiologicalBiologyCD8B1 geneCXCL13 geneCessation of lifeChildChronicChronic HepatitisChronic Hepatitis BDataDefectDevelopmentDiseaseDisease OutcomeDouble Stranded DNA VirusEffectivenessEffector CellEnvironmentEventGenerationsGoalsHelper-Inducer T-LymphocyteHepaticHepatitis BHepatitis B VirusHumanImmuneImmune System DiseasesImmune responseImmune systemImmunityImmunologicsImmunologyIndividualInfectionInjuryLaboratoriesLeadLigandsLightLiverLiver FailureLiver diseasesLocationLymphocyteMalignant neoplasm of liverMediatingModelingMotionMusNeonatalNewborn InfantPathogenesisPatientsPatternPhenocopyPlasmidsPredisposing FactorPrimary carcinoma of the liver cellsProcessProductionRag1 MouseResearchRoleSerologicalSignal TransductionSiteSplenocyteStagingSystemT-LymphocyteTestingTherapeuticTherapeutic InterventionTimeTissuesTransgenic MiceTransgenic ModelTransgenic OrganismsUnited StatesViralViral AntigensVirusVirus DiseasesWorkage relatedbasechemokinechemokine receptorhuman diseaseimmune activationinterleukin-21interleukin-21 receptorintrahepaticliver biopsymolecular markermouse modelneonatenew therapeutic targetnovelpathogenpreventprogramsreceptorreconstitutionresearch studyresponsesuccesstherapeutic targettooltraffickingyoung adult

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