Mouse Models for the Functional Analysis of Asthma-Associated Human Polymorphisms

用于哮喘相关人类多态性功能分析的小鼠模型

• 批准号: 8310328
• 负责人: Donata Vercelli
• 金额: $ 37.88万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-18 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8310328
• 关键词: Affect; Allergens; Allergic; Allergic Disease; Allergic inflammation; Asthma; Bacterial Artificial Chromosomes; Biological; CD4 Positive T Lymphocytes; Caucasians; Caucasoid Race; Child; Cytokine Gene; Detection; Disease susceptibility; Employee Strikes; Enrollment; Event; Exhibits; Extrinsic asthma; Gene Expression; Genes; Genetic Polymorphism; Genetic Transcription; Genetic Variation; Genomics; Genotype; Goals; Haplotypes; Human; Hypersensitivity; IL13 gene; IL4 gene; IL5 gene; IgE; Immune; In Vitro; Infant; Interleukin-13; Interleukin-4; Link; Lung; Lung Inflammation; Mediating; Modeling; Mus; Pathogenesis; Pathology; Pathway interactions; Patients; Pattern; Phenotype; Physiological; Physiology; Play; Population; Population Heterogeneity; Predisposition; Process; Production; Regulation; Research; Role; Single Nucleotide Polymorphism; Th2 Cells; Transgenes; Transgenic Mice; Transgenic Organisms; Variant; Work; base; cis acting element; cytokine; gene function; genetic variant; in vitro Model; in vivo; in vivo Model; mast cell; mouse model; novel; overexpression; promoter; reconstitution; response