The Control of T Cell Development in Responses by PTEN

PTEN 对 T 细胞发育反应的控制

• 批准号: 8311931
• 负责人: Laurence A Turka
• 金额: $ 35万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8311931
• 关键词: 1-Phosphatidylinositol 3-Kinase; Age; Animals; Apoptotic; Area; Autoantibodies; Autoimmune Diseases; Autoimmune Process; Autoimmunity; Binding; CD28 gene; CD4 Positive T Lymphocytes; Cancer Cell Growth; Cell Death; Cell Lineage; Cell Nucleus; Cell physiology; Cells; Centromere; Cessation of life; Chromosomal Stability; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 14; Cytokine Receptors; DNA Double Strand Break; Data; Defect; Development; Equilibrium; Event; Gene Targeting; Generations; Genes; Genome; Genome Stability; Goals; Growth Factor Receptors; Homeostasis; Immune Tolerance; Immune response; Immune system; In Vitro; Infection; Interleukin-2; Intrinsic factor; Laboratories; Lipids; Lymphoma; Maintenance; Malignant - descriptor; Maps; Mature T-Lymphocyte; Mediating; Mind; Modeling; Mus; Nuclear; PTEN gene; Peripheral; Phase; Phosphoric Monoester Hydrolases; Population; Predisposition; Prevention; Proliferating; Reaction; Receptor Signaling; Regulatory T-Lymphocyte; Reporter; Research; Role; Self Tolerance; Signal Transduction; Staging; Syndrome; T cell response; T-Cell Development; T-Cell Lymphoma; T-Lymphocyte; TCR Activation; Testing; Thymus Gland; Transgenic Mice; Tumor Suppressor Genes; V(D)J Recombination; base; c-myc Genes; cell behavior; centromere protein C; in vivo; insight; interest; mutant; prevent; receptor; response; tumor; tumor growth