MOLECULAR REGULATION OF HDL METABOLISM & REVERSE CHOLESTEROL TRANSPORT

HDL 代谢的分子调控

• 批准号: 8147395
• 负责人: Daniel James Rader
• 金额: $ 33.93万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2013-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8147395
• 关键词: Address; Adopted; Affect; Apolipoproteins A; Atherosclerosis; Biological Assay; C-terminal; CETP gene; Cardiovascular system; Cells; Chemicals; Cholesterol; Cholesterol Esters; Collaborations; Complement; Data; Development; Diet; Esterification; Gene Expression; Hepatic; High Density Lipoprotein Cholesterol; High Density Lipoproteins; Human; Hybrids; Hydrophobicity; In Vitro; Investigation; Knock-out; Knockout Mice; Link; Lipid Binding; Liver; Low Density Lipoprotein Receptor; Measures; Mediating; Metabolism; Methods; Modeling; Molecular; Mus; Mutation; N-terminal; Peripheral; Phenotype; Phosphatidylcholine-Sterol O-Acyltransferase; Phospholipids; Phytosterols; Plasma; Play; Property; Proteins; Publishing; Radiolabeled; Regulation; Reticuloendothelial System; Role; Sterols; Structure; Tangier Disease; Therapeutic; Tissues; Tracer; Variant; Wild Type Mouse; base; expression vector; familial cholesteryl ester deficiency; in vivo; in vivo Model; inhibitor/antagonist; insight; intravenous injection; macrophage; mortality; novel; novel therapeutic intervention; overexpression; programs; radiotracer; receptor expression; research study; reverse cholesterol transport; species difference; tool; torcetrapib; uptake; vector