CB: Pathology and Tissue Procurement Core

病理学和组织采购核心的具体目标是： 目标1维护和增强肿瘤组织和匹配血液样本的存储库 中枢神经系统(CNS)肿瘤患者在加州大学接受治疗 德克萨斯州安德森癌症中心(UTMDACC)。 目的2提供孢子所用组织样本的全面组织学特征 项目，包括患者标本和动物实验性肿瘤； 尽快将组织样本分发给孢子调查员进行分析；并提供 对对孢子内组织切片进行的研究进行解释的专门知识 项目。 目标3提供集中服务，包括生物标记物的免疫组织化学表征， 组织阵列的设计和构建，以及肿瘤样本的原代培养 恰如其分。 目标4支持一个全面的、前瞻性的交互数据库，其中包含详细的临床和 在UTMDACC接受护理或评估的中枢神经系统肿瘤患者的病理数据。 目的5通过共享组织资源促进孢子间的协作。

The specific objectives of the Pathology and Tissue Procurement Core are to: Objective 1 Maintain and enhance a repository of tumor tissue and matched blood specimens from patients with central nervous system (CNS) tumors receiving care at The University of Texas M. D. Anderson Cancer Center (UTMDACC). Objective 2 Provide comprehensive histologic characterization of tissue samples used in the SPORE Projects, including specimens from patients and experimental tumors in animals; expeditiously distribute tissue specimens to SPORE investigators for analysis; and provide expertise in the interpretation of studies performed on tissue sections within the SPORE Projects. Objective 3 Offer centralized services, including immunohistochemical characterization of biomarkers, tissue array design and construction, and primary culture of tumor samples where appropriate. Objective 4 Support a comprehensive, prospective interactive database with detailed clinical and pathologic data for patients with CNS tumors receiving care or evaluation at UTMDACC. Objective 5 Facilitate inter-SPORE collaborations through sharing of tissue resources.