International Cerebrovascular Translational Clinical Research Training Program

描述(由申请者提供)：阿加汗大学的国际脑血管转化性临床研究培训计划(ICTCRT)是一个基础广泛的多学科和多国培训计划，其毕业生将拥有进行与巴基斯坦需求相关和适用的中风临床研究的知识、技能和能力。这一目标将通过一项为期三年的培训计划来实现，该计划的第一年将致力于获得独立评估和管理中风患者所需的临床技能，以及批判性地评估现有中风证据及其与发展中国家的相关性的认知技能。第二年和第三年将是研究年，学员将在这两年完成临床研究硕士学位，并开发和执行脑血管研究项目。该项目将尊重已确定的具有国家相关性和影响力的研究主题。将为受训者指派一名国际项目教员，其专业知识和经验与受训者开发的项目相辅相成。除了正在进行的当地评估外，该计划还将每年由一个国际“培训咨询小组”进行审查。ICTCRT计划具有显著的“附加值”。它已经从地区性Cochrane网络、Fogarty国际生物伦理计划以及Fogarty紧急情况和创伤网络获得了培训和监测责任以及课程开发的承诺。阿加汗大学医学研究生教育认可了“中风奖学金”，这是巴基斯坦于2009年发起的第一项奖学金。受训者将有机会接触和研究一个全面的中风生物资源，该资源目前正在招募来自巴基斯坦各地的患者，通过奖励和持续的赠款成为可能。ICTCRT计划将招收学员，不分背景或性别。除了能力之外，在巴基斯坦成功留任的指标将增加被选入这一令人兴奋的机会的机会。 公共卫生相关性：迫切需要创造必要的人力资源，以抗击南亚中风这一非传染性疾病的流行。预计南亚可归因于中风的死亡率和发病率的增长幅度将远远超过世界上任何其他地理区域。巴基斯坦没有针对中风的正式培训或研究计划。ICTCRT计划将满足这一迫切需求。

DESCRIPTION (provided by applicant): The International Cerebrovascular Translational Clinical Research Training Program (ICTCRT) at the Aga Khan University is a broad based multidisciplinary and multinational training program whose graduates will have the knowledge, skills and aptitude to perform clinical research on stroke which has relevance and applicability to the needs of Pakistan. This goal will be achieved by a three year training program whose first year will be dedicated to the acquisition of clinical skills needed to evaluate and manage stroke patients independently and the cognitive skills to critically evaluate the current evidence on stroke and its relevance to developing countries. The second and third year will be research years where the trainee will complete a Masters in Clinical Research and develop and execute a cerebrovascular research project. This project will respect an identified research theme of national relevance and impact. An international program faculty will be assigned to the trainee whose expertise and experience complement the project developed by the trainee. The program be reviewed annually by a international" Training Advisory Group" in addition to ongoing local evaluation. The ICTCRT program has significant "added value". It has secured commitment of training and monitoring responsibilities and course development from the regional Cochrane network, the Fogarty International Bioethics Program and the Fogarty Emergency and Trauma network nationally. The Aga Khan University Postgraduate Medical Education has recognized a "stroke fellowship" the first in Pakistan to be initiated in 2009. The trainee will have access and research opportunities enabled by a comprehensive stroke bio-resource which is currently enrolling patients from all over Pakistan, made possible through awards and ongoing grants. The ICTCRT program will recruit trainees regardless of their background or gender. In addition to ability, indicators of successful retention within Pakistan will increase the chances of being selected for this exciting opportunity. PUBLIC HEALTH RELEVANCE: There an urgent need to create the human resource necessary to combat the noncommunicable disease epidemic of stroke in South Asia. The projected increase in mortality and morbidity attributable to stroke is expected to be much greater in South Asia than any other geographical area worldwide. There are no formal training or research programs for stroke in Pakistan. The ICTCRT program will fulfill this urgent need.