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Combined effects of alcohol and caffeine on agency judgment, impulsivity and risk

酒精和咖啡因对机构判断、冲动和风险的综合影响

基本信息

批准号：
7993039
负责人：
Adrienne Julie Heinz
金额：
$ 3.05万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-12-01 至 2011-08-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7993039
关键词：
Affect Affective Alcohol consumption Alcohol or Other Drugs use Alcoholic Beverages Alcoholic Intoxication Alcohols Area Behavioral Caffeine Clinical Clinical Competence Cognitive Data Data Analyses Development Double-Blind Method Drug Combinations Etiology Expectancy Faculty Fostering Goals Health Impaired cognition Impulsive Behavior Impulsivity Individual Intoxication Judgment Knowledge Laboratory Study Literature Measures Mentors Methodology Motivation Outcome Participant Performance Pharmaceutical Preparations Placebo Effect Positioning Attribute Psychology Psychomotor Performance Public Health Questionnaires Randomized Reporting Research Research Project Grants Research Training Risk Risk Behaviors Risk-Taking Scientist Self-control as a personality trait Series Staging Substance Use Disorder Training Training Programs Woman addiction alcohol effect behavioral pharmacology career computerized design expectation experience indexing men novel risk perception skills social

项目摘要

DESCRIPTION (provided by applicant): The overall goal of the proposed training plan is to further develop my knowledge and research skills in the areas of substance use and health risk behaviors and to integrate this with an understanding of behavioral pharmacology methodology and data analysis. This experience will also foster my development as a scientist-practitioner such that my research and clinical training will ultimately inform future research on the etiology and treatment of substance use disorders and related health issues. Toward these ends, the candidate has designed a research project that involves mentored, didactic, and experiential research and clinical training across three primary areas: 1) Addiction, 2) Health Risk Behaviors, and 3) Clinical Competence. The applicant aims to build on previous training in substance use and cognitive mechanisms of health risk behaviors to conduct a dissertation project that unites these two areas in a novel direction. The project would be an important step in achieving my career goal to pursue a faculty position in an academic psychology department where I will carry out independent research and supervise trainees. The general aim of the proposed research training program is to delineate a clear profile of the conjoint effects of alcohol and caffeine on critical affective, behavioral, and cognitive outcomes in young social drinkers. The motivation for examining this particular drug combination comes from a burgeoning yet small literature on the conjoint effects of caffeine and alcohol on subjective intoxication and psychomotor performance. These studies collectively demonstrate that although caffeine only mildly antagonizes the effects of alcohol, individuals nonetheless feel less impaired, and report being more likely to drive or continue to drink alcohol. This observation may be explained either by the pharmacological effects of caffeine or by individuals' expectations for caffeine to counteract the untoward effects of alcohol. The proposed project aims to examine whether: 1) caffeine offsets the effects of alcohol on indices of risk behavior, personal agency (self- control), and impulsivity and 2) outcome expectancies for caffeine influences these outcomes. Behavioral data will include performance on a series of computerized tasks assessing risk taking and risk perception, impulsivity, and judgments of agency. Participants will also complete a battery of questionnaires that will measure expectations for alcohol and caffeine, and state affect among other important constructs. Data will be collected from 128 men and women in a randomized controlled, double-blind laboratory study. We predict that individuals who drink alcohol and caffeine will manifest less risky and impulsive behavior to the extent that caffeine does, or is expected to, mitigate the cognitive impairments induced by alcohol and increase accuracy of judgments of agency. This area of research is in its nascent stages and is sorely needed given the popularity of caffeinated alcoholic beverages. Accordingly, this study will be one of the first to evaluate the conjoint effects of these drugs on health-risk behaviors and findings may inform public health efforts.

描述（由申请人提供）：拟议培训计划的总体目标是进一步发展我在物质使用和健康风险行为领域的知识和研究技能，并将其与行为药理学方法和数据分析的理解相结合。这一经验也将促进我作为一个科学家，实践者的发展，使我的研究和临床培训将最终通知未来的病因学和物质使用障碍和相关健康问题的治疗研究。为此，候选人设计了一个研究项目，涉及三个主要领域的指导，教学和体验式研究和临床培训：1）成瘾，2）健康风险行为，3）临床能力。申请人的目标是建立在物质使用和健康风险行为的认知机制以前的培训，进行一个论文项目，在一个新的方向团结这两个领域。这个项目将是实现我的职业目标的重要一步，我将在一个学术心理学系担任教职，在那里我将进行独立研究并监督学员。拟议的研究培训计划的总体目标是描绘一个清晰的轮廓，酒精和咖啡因对关键的情感，行为和认知结果在年轻的社交饮酒者的联合影响。研究这种特殊药物组合的动机来自于一个新兴的但很少的文献，关于咖啡因和酒精对主观醉酒和精神表现的联合作用。这些研究共同表明，尽管咖啡因只能轻微地对抗酒精的影响，但个人仍然感觉受到的损害较小，并报告更有可能开车或继续饮酒。这一观察结果可以用咖啡因的药理作用或个人对咖啡因抵消酒精不良影响的期望来解释。拟议的项目旨在研究：1）咖啡因是否抵消酒精对风险行为，个人代理（自我控制）和冲动指数的影响; 2）咖啡因的结果预期是否影响这些结果。行为数据将包括一系列计算机化任务的表现，评估风险承担和风险感知，冲动性和对机构的判断。参与者还将完成一系列问卷，这些问卷将测量对酒精和咖啡因的期望，并在其他重要结构中陈述影响。将在一项随机对照、双盲实验室研究中从128名男性和女性中收集数据。我们预测，饮用酒精和咖啡因的个体将表现出较少的风险和冲动行为，咖啡因确实或预计会减轻酒精引起的认知障碍，并提高对代理的判断准确性。这一领域的研究正处于起步阶段，鉴于含咖啡因的酒精饮料的流行，这一领域的研究非常必要。因此，这项研究将是第一个评估这些药物对健康风险行为的联合作用的研究，研究结果可能会为公共卫生工作提供信息。