RCMI Program at the Ponce School of Medicine

庞塞医学院 RCMI 项目

• 批准号: 8007416
• 负责人: Raul A Armstrong
• 金额: $ 239.69万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-25 至 2013-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8007416
• 关键词: RCMI; Program; Ponce; Medicine

DESCRIPTION (provided by applicant): Since its inception in 1985, the RCMI Program has been instrumental in shifting the institution from a traditional teaching school to a vigorous research center. The institution has experienced a substantial development of its human as well as its physical infrastructure. Along these lines, through auspices of the RCMI Program, the institution has been able to acquire state-of-the-art facilities, equipment, and other resources, required to pursue competitive basic, clinical, and behavioral research. Some of the research areas developed include; Retrovirology, HIV/AIDS, Molecular Biology, Human and Bacterial Genetics, Protein Chemistry and Enzymology, Immunology, Cancer Biology, and Epidemiology. As a direct impact of this development, the institution experienced a substantial improvement in; the number and quality of peer-reviewed manuscripts elicited by the faculty, the number of scientific presentations at competitive forums at the national as well as international levels, and in the number of submitted and funded research and research training initiatives. The RCMI Program, through the period of years 2008-2013, proposes to continue the development of its human and physical infrastructure in order for the institution to reach its major goals and objectives contained in the Institutional Strategic Plan for Research. Particular emphasis will be given to the development of health disparities research in Puerto Rico and the Caribbean Basin, and the development of translational research. The proposed Program consists of four Core activities (Administration, AIDS Research Infrastructure Program, Molecular Biology, and Behavioral) and five Research Pilot Projects. The major goals and objectives of the present competitive continuation application are to; (1) provide administrative support to foster continued progress of RCMI Program activities, (2) implement a formal Faculty Mentoring Program to assist investigators in developing independent and competitive research careers, (3) strengthen faculty member recruitment, development, and retention, (4) strengthen the HIV/AIDS Research Infrastructure Program and the Molecular Biology Core, (5) implement and further develop a Behavioral Neurosciences Core, (6) provide the necessary leadership and guidance for the development of five Research Pilot Projects presented by junior faculty members, and (7) implement a comprehensive evaluation program to provide continuous assessment of progress achieved by all RCMI Program activities.

描述(由申请人提供)：自1985年成立以来，RCMI计划一直在帮助学校从传统的教学学校转变为一个充满活力的研究中心。该机构的人力和物质基础设施都有了长足的发展。沿着这些思路，通过RCMI计划的赞助，该机构已经能够获得进行竞争性基础、临床和行为研究所需的最先进的设施、设备和其他资源。发展的研究领域包括：逆转录病毒学、艾滋病毒/艾滋病、分子生物学、人类和细菌遗传学、蛋白质化学和酶学、免疫学、癌症生物学和流行病学。作为这一发展的直接影响，该机构在以下方面有了很大的改进：由教员提出的同行评议手稿的数量和质量，在国家和国际一级竞争性论坛上的科学陈述数量，以及提交和资助的研究和研究培训倡议的数量。在2008-2013年期间，RCMI方案建议继续发展其人力和物质基础设施，以使该机构实现其研究机构战略计划中所载的主要目标和目的。将特别重视在波多黎各和加勒比盆地开展健康差距研究，以及开展转化性研究。拟议的计划包括四个核心活动(行政管理、艾滋病研究基础设施计划、分子生物学和行为学)和五个研究试点项目。本竞争性续展申请的主要目的和目的是；(1)提供行政支持，以促进RCMI计划活动的持续进展，(2)实施正式的教师指导计划，以帮助研究人员发展独立和有竞争力的研究职业，(3)加强教员的招聘、发展和留住，(4)加强艾滋病毒/艾滋病研究基础设施计划和分子生物学核心，(5)实施并进一步发展行为神经科学核心，(6)为由初级教员提出的五个研究试点项目的发展提供必要的领导和指导，以及(7)实施综合评估计划，以对所有RCMI计划活动所取得的进展进行持续评估。

项目成果

The effect of sympathy on discriminatory attitudes toward persons living with HIV/AIDS in Puerto Rico: a hierarchical analysis of women living in public housing.

同情对在波多黎各的艾滋病毒/艾滋病的人的歧视态度的影响：对居住在公共住房中的妇女的等级分析。

• DOI: 10.1080/09540120801932199
• 发表时间: 2009-02
• 期刊: AIDS care
• 影响因子: 1.7
• 作者: Norman LR;Abreu S;Candelaria E;Sala A
• 通讯作者: Sala A

Reactivity of anti-Blomia tropicalis IgG and IgE in patients with atopic dermatitis.

特应性皮炎患者抗热带布洛米亚 IgG 和 IgE 的反应性。

• DOI: 10.1046/j.1365-2230.2002.01029.x
• 发表时间: 2002
• 期刊: Clinical and experimental dermatology
• 影响因子: 4.1
• 作者: Pires,MC;Calux,MJF;Mori,JC;Montealegre,F
• 通讯作者: Montealegre,F

The role of DNA repair capacity in melanoma skin cancer risk in a population chronically exposed to high levels of sunlight.

DNA 修复能力在长期暴露于高强度阳光下的人群中黑色素瘤皮肤癌风险中的作用。

• 发表时间: 2010
• 期刊: The Ochsner journal
• 作者: Matta,JaimeL;Rodriguez,Giovanna;Villa,Jaime;Ruiz,Abigail
• 通讯作者: Ruiz,Abigail

Prediction of warfarin dose reductions in Puerto Rican patients, based on combinatorial CYP2C9 and VKORC1 genotypes.

基于 CYP2C9 和 VKORC1 组合基因型预测波多黎各患者华法林剂量减少。

• DOI: 10.1345/aph.1q190
• 发表时间: 2012
• 期刊: The Annals of pharmacotherapy
• 作者: Valentin,IsaIvette;Vazquez,Joan;Rivera-Miranda,Giselle;Seip,RichardL;Velez,Meredith;Kocherla,Mohan;Bogaard,Kali;Cruz-Gonzalez,Iadelisse;Cadilla,CarmenL;Renta,JessicaY;Feliu,JuanF;Ramos,AlgaS;Alejandro-Cowan,Yirelia;Gorowski
• 通讯作者: Gorowski

Immediate-Early (IE) gene regulation of cytomegalovirus: IE1- and pp71-mediated viral strategies against cellular defenses.

• DOI: 10.1007/s12250-014-3532-9
• 发表时间: 2014-12
• 期刊: Virologica Sinica
• 影响因子: 5.5
• 作者: Torres L;Tang Q
• 通讯作者: Tang Q