COBRE: MUSC: CORE B: BIOSTATISTICS CORE

COBRE：MUSC：核心 B：生物统计学核心

• 批准号: 8167763
• 负责人: Elizabeth H. Slate
• 金额: $ 38.33万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167763
• 关键词: Applications Grants; Archives; Biostatistical Methods; Biostatistics Core; Calibration; Centers of Research Excellence; Collaborations; Communities; Computer Retrieval of Information on Scientific Projects Database; Data; Data Files; Data Quality; Data Security; Databases; Development; Documentation; Funding; Future; Grant; Growth; Institution; Maintenance; Mentors; Methods; Oral health; Preparation; Publications; Randomized; Reporting; Research; Research Infrastructure; Research Personnel; Resources; Scheme; Site; Source; Statistical Study; United States National Institutes of Health; data management; design; programs; quality assurance; scientific computing

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Biostatistics Core is a critical component of the infrastructure supporting the initiation, growth and sustenance of oral health researchers at MUSC. Core B activities are focused on the following four aims: (1) statistical collaboration, including assistance with design of new studies; preparation of grant proposals; randomization and blinding schemes for calibration studies; statistical analyses and associated reports; and assistance in the integration of statistical interpretations into scientific conclusions and publications; (2) data management, including design, implementation and maintenance of databases, data entry and methods for data transfer from remote sites to MUSC; a program of data quality assurance; documentation of data files for ease of accessibility in the future; and data security and archiving of data files for long-term storage; (3) mentoring in biostatistical methods for all COBRE investigators, including mentoring of a junior biostatistician in collaboration and methods relevant to oral health research; and (4) development of new biostatistical methods as needed for specific projects and transfer of recent biostatistical methods to the oral health research community. Additionally, Core B established and maintains a scientific computing infrastructure for COBRE investigators.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 生物统计学核心是支持MUSC口腔健康研究人员启动，成长和维持的基础设施的重要组成部分。 核心B活动侧重于以下四个目标： (1)统计合作，包括协助设计新的研究;编写赠款提案;校准研究的随机化和盲法计划;统计分析和相关报告;协助将统计解释纳入科学结论和出版物; (2)数据管理，包括数据库的设计、实施和维护、数据输入以及从远程站点向MUSC传输数据的方法;数据质量保证方案;数据文件的记录，以便于将来访问;以及数据安全和数据文件的存档，以供长期存储; (3)为所有COBRE研究者提供生物统计学方法方面的指导，包括指导一名初级生物统计学家与口腔健康研究相关的方法;以及 (4)根据具体项目的需要开发新的生物统计方法，并将最新的生物统计方法转移到口腔健康研究界。 此外，核心B为COBRE调查人员建立并维护了科学计算基础设施。