INTER-SITE QA DEVELOPMENT FOR THE FIRST BIRN

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 FIRST（功能成像研究精神分裂症试验床）生物医学信息学研究网络（fBIRN） 该项目是有史以来第一个大规模、多中心的精神分裂症功能磁共振成像研究（http：www.nbirn.net）。FBIRN项目 将汇集来自11个参与站点的功能磁共振成像数据，以获得大量不同的研究人群 in a modern适度time period期间.我们的中心一直负责校准和质量保证方面的重要性， 多中心fMRI试验，G.格洛弗在fBIRN内主持校准工作组。 该子项目是一项研究，使用屏气（BH）来校准和减轻以下因素的混杂效应： 受试者之间的血流动力学差异，从而减少方差并提高在大样本中汇总数据的能力。 人口。以前的活动已经制定了基本方法，该集团目前正在使用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The FIRST (Functional Imaging Research Schizophrenia Testbed) Biomedical Informatics Research Network (fBIRN) program is the first-ever large scale, multi-center fMRI study of schizophrenia (http://www.nbirn.net). The fBIRN project will pool fMRI data from each of the 11 participating sites to enable the acquisition of a large and diverse study population in a modest time period. Our Center has been responsible for the calibration and quality assurance aspects important for multi-center fMRI trials, and G. Glover chairs the Calibration Working Group within the fBIRN. This subproject is a study of the use of breath holding (BH) to calibrate and mitigate the confounding effects of hemodynamic differences between subjects, thereby reducing variance and improving the ability to pool data across large populations. Previous activities have developed the basic method, which is in current use by the consortium.