INTER-SITE QA DEVELOPMENT FOR THE FIRST BIRN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 第一个(功能成像研究精神分裂症试验床)生物医学信息学研究网络(FBIRN) 该计划是有史以来第一个大规模、多中心的精神分裂症(http://www.nbirn.net).)功能磁共振研究FBIRN项目 将汇集来自11个参与站点的每个站点的功能磁共振数据，以支持获取大量和多样化的研究人群 在一段适度的时间内。我们的中心一直负责重要的校准和质量保证方面的工作 G·格洛弗担任fBIRN内校准工作组的主席。 这个子项目是一项关于屏气(BH)的研究，以校准和减轻 受试者之间的血流动力学差异，从而减少差异并提高跨大型数据库共享数据的能力 人口。以前的活动已经制定了基本方法，该联盟目前正在使用这种方法。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The FIRST (Functional Imaging Research Schizophrenia Testbed) Biomedical Informatics Research Network (fBIRN) program is the first-ever large scale, multi-center fMRI study of schizophrenia (http://www.nbirn.net). The fBIRN project will pool fMRI data from each of the 11 participating sites to enable the acquisition of a large and diverse study population in a modest time period. Our Center has been responsible for the calibration and quality assurance aspects important for multi-center fMRI trials, and G. Glover chairs the Calibration Working Group within the fBIRN. This subproject is a study of the use of breath holding (BH) to calibrate and mitigate the confounding effects of hemodynamic differences between subjects, thereby reducing variance and improving the ability to pool data across large populations. Previous activities have developed the basic method, which is in current use by the consortium.