TSENSE ACCELERATED BILATERAL 3D SPIRAL BREAST IMAGING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：动态增强乳腺MRI对时间分辨率和空间分辨率都有很高的要求。在需要覆盖两个大体积的双侧乳腺成像中，为了提高时间分辨率，我们结合了快速3D螺旋成像和时间敏感性编码(TSENSE)加速。 方法：使用双波段光谱-空间脉冲刺激双侧乳房，以提供稳健的脂肪抑制和每个乳房体积的独立空间和光谱轮廓。“螺旋堆叠”成像轨迹用于k空间的快速采集。我们通过在平板方向上应用TSENSE来加快成像速度。 在时间范围内，所有偶数kz平面先于所有奇数kz平面获得。奇数帧和偶数帧一起可用于估计线圈灵敏度函数。然后，敏感度编码(SENSE)可以用来填充奇数和偶数集合中缺失的平面，从而将帧速率加速两倍。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. PURPOSE: Dynamic contrast breast MRI requires both high temporal and spatial resolution. To increase temporal resolution in bilateral breast imaging which needs to cover two large volumes, we combine rapid 3D spiral imaging and temporal sensitivity-encoding (TSENSE) acceleration. METHODS: A dual-band spectral-spatial pulse was used to excite both breasts for providing robust fat suppression and an independent spatial and spectral profile for each breast volume. The "stack-of-spirals" imaging trajectory was used for a rapid k-space acquisition. We accelerated an imaging speed by applying TSENSE in the slab direction. All even kz-planes are acquired before all odd kz-planes for time frame. The odd and even frames together can be used to estimate coil sensitivity functions. Then sensitivity-encoding (SENSE) can be used to fill in missing planes in both the odd and even sets, to accelerate the frame rate by a factor of two.