TSENSE ACCELERATED BILATERAL 3D SPIRAL BREAST IMAGING

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 目的：动态对比乳腺MRI需要高的时间和空间分辨率。为了提高双侧乳腺成像的时间分辨率，需要覆盖两个大体积，我们结合了联合收割机快速3D螺旋成像和时间灵敏度编码（TSENSE）加速。 方法：双波段光谱-空间脉冲用于激励两个乳房，以提供稳健的脂肪抑制和每个乳房体积的独立空间和光谱轮廓。“螺旋堆叠”成像轨迹用于快速k空间采集。我们通过在板方向上应用TSENSE来加快成像速度。 对于时间帧，在所有奇数kz平面之前采集所有偶数kz平面。 奇数帧和偶数帧可以一起用于估计线圈灵敏度函数。 然后，灵敏度编码（SENSE）可以用于填充奇数和偶数集合中的缺失平面，以将帧速率加速两倍。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. PURPOSE: Dynamic contrast breast MRI requires both high temporal and spatial resolution. To increase temporal resolution in bilateral breast imaging which needs to cover two large volumes, we combine rapid 3D spiral imaging and temporal sensitivity-encoding (TSENSE) acceleration. METHODS: A dual-band spectral-spatial pulse was used to excite both breasts for providing robust fat suppression and an independent spatial and spectral profile for each breast volume. The "stack-of-spirals" imaging trajectory was used for a rapid k-space acquisition. We accelerated an imaging speed by applying TSENSE in the slab direction. All even kz-planes are acquired before all odd kz-planes for time frame. The odd and even frames together can be used to estimate coil sensitivity functions. Then sensitivity-encoding (SENSE) can be used to fill in missing planes in both the odd and even sets, to accelerate the frame rate by a factor of two.