Project 5: Nanothecnology-Based Environmental Sensing

项目5：基于纳米技术的环境传感

• 批准号: 8063134
• 负责人: CATHERINE P. KOSHLAND
• 金额: $ 35.12万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8063134
• 关键词: Adsorption; Antibodies; Antigens; Arsenic; Behavior; Binding; Biological; Bioremediations; Carbon Nanotubes; Characteristics; Chemicals; Complex; Detection; Devices; Electronics; Electrons; Elements; Environment; Environmental Monitoring; Environmental Pollution; Evolution; Gases; Gold; Grant; Hazardous Chemicals; Hazardous Substances; Health; Heavy Metals; Intervention; Lasers; Lead; Link; Measurement; Measures; Mercury; Methods; Molecular; Monitor; Morphology; Nanotubes; Optics; Organism; Phase; Process; Property; Raman Spectrum Analysis; Research; Risk; Shapes; Source; Spectrum Analysis; Structure; Superfund; Surface; Techniques; Technology; base; cell type; cost; electrical property; electronic structure; improved; microbial; nanometer; nanoparticle; nanoscale; nanostructured; novel; physical property; remediation; sensor; superfund site

There remains a compelling need for improved ways to detect and quantify toxic and/or hazardous chemical species found at existing or potential Superfund sites. Better analytical techniques could reduce the cost of monitoring, help improve remediation methods, and more accurately assess the health risks associated with hazardous and toxic species. We have developed methods to produce novel nanoparticles, arrays, and structures that could be used for chemical analysis, and propose here several approaches that combine evolving methods with the characterization and monitoring needs of Superfund. They are linked by their use of small scale properties to develop new methods that should be faster, easier, smaller, and/or less expensive. The technologies on which we will focus could ultimately lead to a number of nanometer-based devices which are portable and robust, and which can be employed at commercial facilities or in-the-field for environmental monitoring. Our specific aims are to : 1. Develop low-cost sensors and sensor arrays for measuring chemical species such as arsenic and mercury using nanoparticle properties that can be probed optically and electronically. 2. Develop methods to identify biomolecules (specific antibodies/antigens used in bioremediation) by probing their unique local electronic structure using electron tunneling. 3. Investigate the use of new manufactured nanostructured materials for molecular detection, including structures such as carbon nanotubes and coated nanoparticles. The aims are divided into four tasks: Gas Phase Detection of Heavy Metals Using Nanoparticle Complexes with Laser Fragmentation Spectroscopy, Mercury Detection with Gold Nanoparticles, Surface Enhanced Raman Spectroscopy Detection of Arsenic Species, and the Detection of Bioremediation Organisms using Electronic Cell Typing. This project will investigate using the different and sometimes unique behavior of materials as their size shrink below 100 nm to develop new methods to detect chemical and biological species found at existing or potential Superfund sites. New sensors could reduce the cost of monitoring, help improve remediation methods, and more accurately assess the health risks associated with hazardous and toxic species.

仍然有迫切的需求 改进了检测和量化在现有或 潜在的超级基金网站。更好的分析技术可以降低监测成本，有助于改善 补救方法，并更准确地评估与危险和有毒物质相关的健康风险 物种。我们已经开发出方法来生产新的纳米粒子、阵列和结构，这些可以 用于化学分析，并在此提出了几种将进化方法与 描述和监控超级基金的需求。它们通过使用小规模的属性而联系在一起 开发应该更快、更容易、更小和/或更便宜的新方法。上的技术 我们将重点关注的是最终可能导致许多基于纳米的设备，这些设备是便携式和 坚固耐用，可用于商业设施或现场环境监测。我们的 具体目标是：1.开发低成本传感器和传感器阵列，用于测量化学物质 作为砷和汞，使用纳米粒子的性质，可以用光学和电子手段探测。2. 开发通过探测来识别生物分子(用于生物修复的特定抗体/抗原)的方法 它们独特的局域电子结构利用电子隧穿。3.调查新制造产品的使用情况 用于分子检测的纳米结构材料，包括碳纳米管和 包覆的纳米颗粒。目标分为四个方面的任务：重金属的气相检测 纳米颗粒络合物的激光碎裂光谱研究--金检测汞 纳米颗粒，表面增强拉曼光谱检测砷的形态，以及检测 使用电子细胞分型的生物修复生物体。 这个项目将研究使用不同的，有时是独特的材料行为作为他们的大小 缩小到100纳米以下，以开发新的方法来检测在现有或 潜在的超级基金网站。新的传感器可以降低监测成本，帮助改善补救措施 方法，更准确地评估与危险和有毒物种有关的健康风险。