FUNCTION PROFILE OF UBIQUITIN RECEPTOR RPN13
FUNCTION PROFILE OF UBIQUITIN RECEPTOR RPN13
批准号:
8168967
负责人:
Kylie J. Walters
金额:
$0.39万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-03-01 至 2011-02-28
关键词:
Computer Retrieval of Information on Scientific Projects DatabaseDegradation PathwayDeubiquitinating EnzymeFundingGrantInstitutionPlayResearchResearch PersonnelResourcesRoleSourceTechniquesUbiquitinUnited States National Institutes of Healthmulticatalytic endopeptidase complexprotein degradationreceptor
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
Rpn13是一种蛋白酶体成分,是一种新发现的泛素受体。Rpn13也是一种脱泛素酶Uch37的蛋白酶体受体。这使得Rpn13在蛋白质降解途径中发挥重要作用。Rpn13的功能谱有望通过现代核磁共振技术得到阐明。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Rpn13 is a proteasome component and newly identified as a ubiquitin receptor. Rpn13 is also the proteasomal receptor for a deubiquitinating enzyme Uch37. These make Rpn13 playing important roles in protein degradation pathway. The function profile of Rpn13 is expected to be elucidated by using modern NMR techniques.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
NMR Structural Studies of Ubiquitin Receptor Protein Complexes
-
批准号:7990131
-
项目类别:
-
资助金额:$18.01万
-
财政年份:2010
-
负责人:Kylie J. Walters
-
依托单位:
NMR Structural Studies of Ubiquitin Receptor Protein Complexes
-
批准号:8104087
-
项目类别:
-
资助金额:$32.67万
-
财政年份:2010
-
负责人:Kylie J. Walters
-
依托单位:
FUNCTION PROFILE OF UBIQUITIN RECEPTOR S5A
-
批准号:8168953
-
项目类别:
-
资助金额:$0.46万
-
财政年份:2010
-
负责人:Kylie J. Walters
-
依托单位:
NMR Structural Studies of Ubiquitin Receptor Protein Complexes
-
批准号:8403784
-
项目类别:
-
资助金额:$30.53万
-
财政年份:2010
-
负责人:Kylie J. Walters
-
依托单位:
NMR Structural Studies of Ubiquitin Receptor Protein Complexes
-
批准号:8207198
-
项目类别:
-
资助金额:$32.57万
-
财政年份:2010
-
负责人:Kylie J. Walters
-
依托单位:
Defining how the Proteasome Recognizes its Ubiquitylated Substrates
-
批准号:7847348
-
项目类别:
-
资助金额:$4.84万
-
财政年份:2009
-
负责人:Kylie J. Walters
-
依托单位:
FUNCTION PROFILE OF UBIQUITIN RECEPTOR RPN13
-
批准号:7954676
-
项目类别:
-
资助金额:$0.49万
-
财政年份:2009
-
负责人:Kylie J. Walters
-
依托单位:
FUNCTION PROFILE OF UBIQUITIN RECEPTOR S5A
-
批准号:7954637
-
项目类别:
-
资助金额:$1.16万
-
财政年份:2009
-
负责人:Kylie J. Walters
-
依托单位:
FUNCTION PROFILE OF UBIQUITIN RECEPTOR S5A
-
批准号:7721683
-
项目类别:
-
资助金额:$0.28万
-
财政年份:2008
-
负责人:Kylie J. Walters
-
依托单位:
LINKING THE PROTEASOME ACTIVITY TO XPC BINDING PROTEIN HHR23A
-
批准号:7721684
-
项目类别:
-
资助金额:$0.65万
-
财政年份:2008
-
负责人:Kylie J. Walters
-
依托单位:
STRUCTURAL ANALYSIS OF NAT
-
批准号:7721637
-
项目类别:
-
资助金额:$0.26万
-
财政年份:2008
-
负责人:Kylie J. Walters
-
依托单位:
Structural Analysis of NAT Acetylation, Substrate Specificity and Polymorphisms
-
批准号:7489476
-
项目类别:
-
资助金额:$22.02万
-
财政年份:2007
-
负责人:Kylie J. Walters
-
依托单位:
Structural Analysis of NAT Acetylation, Substrate Specificity and Polymorphisms
-
批准号:7880051
-
项目类别:
-
资助金额:$22.02万
-
财政年份:2007
-
负责人:Kylie J. Walters
-
依托单位:
Structural Analysis of NAT Acetylation, Substrate Specificity and Polymorphisms
-
批准号:7652388
-
项目类别:
-
资助金额:$22.02万
-
财政年份:2007
-
负责人:Kylie J. Walters
-
依托单位:
Structural Analysis of NAT Acetylation, Substrate Specificity and Polymorphisms
-
批准号:7258608
-
项目类别:
-
资助金额:$23.92万
-
财政年份:2007
-
负责人:Kylie J. Walters
-
依托单位:
Linking proteasome activity to DNA repair through hHR23
-
批准号:6870249
-
项目类别:
-
资助金额:$24.12万
-
财政年份:2003
-
负责人:Kylie J. Walters
-
依托单位:
Defining how the Proteasome Recognizes its Ubiquitylated Substrates
-
批准号:8244430
-
项目类别:
-
资助金额:$21.72万
-
财政年份:2003
-
负责人:Kylie J. Walters
-
依托单位:
Defining how the Proteasome Recognizes its Ubiquitylated Substrates
-
批准号:8049247
-
项目类别:
-
资助金额:$24.82万
-
财政年份:2003
-
负责人:Kylie J. Walters
-
依托单位:
Linking proteasome activity to DNA repair through hHR23
-
批准号:7045988
-
项目类别:
-
资助金额:$23.53万
-
财政年份:2003
-
负责人:Kylie J. Walters
-
依托单位:
Linking proteasome activity to DNA repair through hHR23
-
批准号:6612123
-
项目类别:
-
资助金额:$23.06万
-
财政年份:2003
-
负责人:Kylie J. Walters
-
依托单位:
海外基金