STREPTAVIDIN-CONTAINING COMPLEXES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，不一定是研究者的机构。 长期目标是设计可通过设计组装的纳米级结构的大分子组件。这里研究的分子复合物代表了一种将含有链霉亲和素的支柱连接到各种对称性的节点分子的方法。我们建议使用cryo-EM来提供工程纳米结构的结构测定。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The long-term objective is to engineer macromolecular components for nanoscale structures that can be assembled by design. The molecular complex under investigation here represents a way to link streptavidin-containing struts to node molecules of various symmetries. We propose to use cryo-EM to provide a structural assay of the engineered nano-structures.