STRUCTURE OF FLAGELLA COMPLEX

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在趋化过程中，细菌的运动是由鞭毛的旋转感决定的。鞭毛的旋转方向由位于细胞膜上的转子控制，这些转子由超过25种不同的蛋白质组成。蛋白质FliM、FliN和FliG构成鞭毛组装的组成部分，它们各自的多个副本形成转子的C-环。目前的努力是为了了解这些蛋白质之间的相互作用并预测它们的复合体的结构。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During chemotaxis, the motion of the bacteria is determined by the sense of rotation of the flagella. The direction of rotation of flagella is controlled by rotors located in the cell membrane which are composed of more than 25 different proteins. Proteins FliM, FliN and FliG form integral part of flagella assembly and multiple copies of each of them form the C-ring of the rotor. Current efforts are directed to understand the interactions between these proteins and predict the structure of their complex.