STRUCTURE OF FLAGELLA COMPLEX

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 在趋化过程中，细菌的运动由鞭毛的旋转方向决定。鞭毛的旋转方向由位于细胞膜中的转子控制，这些转子由超过25种不同的蛋白质组成。蛋白质FliM、FliN和FliG形成鞭毛组装的组成部分，并且它们中的每一个的多个拷贝形成转子的C环。目前的努力是为了了解这些蛋白质之间的相互作用，并预测其复合物的结构。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. During chemotaxis, the motion of the bacteria is determined by the sense of rotation of the flagella. The direction of rotation of flagella is controlled by rotors located in the cell membrane which are composed of more than 25 different proteins. Proteins FliM, FliN and FliG form integral part of flagella assembly and multiple copies of each of them form the C-ring of the rotor. Current efforts are directed to understand the interactions between these proteins and predict the structure of their complex.