STRUCTURAL STUDIES OF EPH RECEPTORS AND EPHRINS
STRUCTURAL STUDIES OF EPH RECEPTORS AND EPHRINS
批准号:
8169221
负责人:
DIMITAR B NIKOLOV
金额:
$4.36万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-04-01 至 2011-03-31
关键词:
中文摘要
这个子项目是许多研究子项目中的一个
由NIH/NCRR资助的中心赠款提供的资源。子项目及
研究者(PI)可能从另一个NIH来源获得了主要资金,
因此可以在其他CRISP条目中表示。所列机构为
研究中心,而研究中心不一定是研究者所在的机构。
我们使用X射线晶体学,结合其他生物物理和生物化学方法,研究Eph受体的结构和功能及其与ephrin配体的相互作用。 我们还研究了Ephs和ephrin与其他结合伙伴,包括亨尼帕病毒细胞附着蛋白的相互作用。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
We use X-ray crystallography, combined with other biophysical and biochemical methods, to study the structure and function of the Eph receptors and their interactions with the ephrin ligands. We also study the interactions of Ephs and ephrins with other binding partners, including the Henipavirus cell-attachment proteins.
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财政年份:2015
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批准号:8363564
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财政年份:2011
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批准号:8361611
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财政年份:2011
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依托单位:
SIGNAL TRANSDUCTION MECHANISMS OF CELL-SURFACE LIGAND-RECEPTOR SYSTEMS
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批准号:7721231
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资助金额:$0.7万
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财政年份:2008
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负责人:DIMITAR B NIKOLOV
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依托单位:
DETERMINATION OF THE STRUCTURE OF APG7 BY MAD
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财政年份:2008
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负责人:DIMITAR B NIKOLOV
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依托单位:
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财政年份:2006
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依托单位:
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项目类别:
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财政年份:2006
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依托单位:
Structural Study of Semaphorins, Neuropilins and Plexins
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项目类别:
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资助金额:$31.64万
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财政年份:2006
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负责人:DIMITAR B NIKOLOV
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依托单位:
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资助金额:$31.91万
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财政年份:2006
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依托单位:
DETERMINATION OF THE STRUCTURE OF APG7 BY MAD
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财政年份:2005
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负责人:DIMITAR B NIKOLOV
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依托单位:
SIGNAL TRANSDUCTION MECHANISMS OF CELL-SURFACE LIGAND-RECEPTOR SYSTEMS
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财政年份:2005
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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批准号:6811153
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项目类别:
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资助金额:$34.26万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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项目类别:
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资助金额:$34.26万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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项目类别:
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资助金额:$35.86万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
海外基金