STRUCTURAL STUDIES OF EPH RECEPTORS AND EPHRINS
STRUCTURAL STUDIES OF EPH RECEPTORS AND EPHRINS
批准号:
8169221
负责人:
DIMITAR B NIKOLOV
金额:
$4.36万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-04-01 至 2011-03-31
关键词:
中文摘要
点击翻译按钮获取中文摘要
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
We use X-ray crystallography, combined with other biophysical and biochemical methods, to study the structure and function of the Eph receptors and their interactions with the ephrin ligands. We also study the interactions of Ephs and ephrins with other binding partners, including the Henipavirus cell-attachment proteins.
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Targeting the alpha secretase ADAM10 for the treatment of Alzheimer's disease
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批准号:10590899
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项目类别:
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资助金额:$26.55万
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财政年份:2022
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依托单位:
Molecular mechanisms of Tie2/Angiopoietin signaling initiation
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批准号:9159077
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资助金额:$44.81万
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财政年份:2016
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依托单位:
Molecular mechanisms of Tie2/Angiopoietin signaling initiation
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批准号:9321086
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项目类别:
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资助金额:$44.81万
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财政年份:2016
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负责人:DIMITAR B NIKOLOV
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依托单位:
Function-blocking anti-ADAM protease antibodies for inhibition of tumorigenesis
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批准号:9024489
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项目类别:
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资助金额:$19.13万
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财政年份:2015
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负责人:DIMITAR B NIKOLOV
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依托单位:
Function-blocking anti-ADAM protease antibodies for inhibition of tumorigenesis
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批准号:8881452
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项目类别:
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资助金额:$22.96万
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财政年份:2015
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负责人:DIMITAR B NIKOLOV
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依托单位:
STRUCTURAL STUDY OF EPH RECEPTORS
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批准号:8363564
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项目类别:
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资助金额:$0.58万
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财政年份:2011
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负责人:DIMITAR B NIKOLOV
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依托单位:
STRUCTURAL STUDIES OF EPH RECEPTORS AND EPHRINS
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批准号:8361611
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项目类别:
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资助金额:$3.47万
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财政年份:2011
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负责人:DIMITAR B NIKOLOV
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依托单位:
SIGNAL TRANSDUCTION MECHANISMS OF CELL-SURFACE LIGAND-RECEPTOR SYSTEMS
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批准号:7721231
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项目类别:
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资助金额:$0.7万
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财政年份:2008
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负责人:DIMITAR B NIKOLOV
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依托单位:
DETERMINATION OF THE STRUCTURE OF APG7 BY MAD
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批准号:7721329
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项目类别:
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资助金额:$1.68万
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财政年份:2008
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负责人:DIMITAR B NIKOLOV
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依托单位:
Novel Small-Molecule Inhibitors of the Tie2/Angiopoietin Interactions and Signali
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批准号:7426768
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项目类别:
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资助金额:$18.8万
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财政年份:2007
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structural Study of Semaphorins, Neuropilins and Plexins
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批准号:7569452
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项目类别:
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资助金额:$31.91万
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财政年份:2006
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structural Study of Semaphorins, Neuropilins and Plexins
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批准号:7195087
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项目类别:
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资助金额:$30.73万
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财政年份:2006
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structural Study of Semaphorins, Neuropilins and Plexins
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批准号:7099212
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项目类别:
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资助金额:$31.64万
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财政年份:2006
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structural Study of Semaphorins, Neuropilins and Plexins
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批准号:7416575
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项目类别:
-
资助金额:$31.91万
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财政年份:2006
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负责人:DIMITAR B NIKOLOV
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依托单位:
DETERMINATION OF THE STRUCTURE OF APG7 BY MAD
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批准号:7181053
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项目类别:
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资助金额:$5.82万
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财政年份:2005
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负责人:DIMITAR B NIKOLOV
-
依托单位:
SIGNAL TRANSDUCTION MECHANISMS OF CELL-SURFACE LIGAND-RECEPTOR SYSTEMS
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批准号:7369522
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项目类别:
-
资助金额:$0.13万
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财政年份:2005
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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批准号:7260289
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项目类别:
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资助金额:$34.63万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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批准号:6811153
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项目类别:
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资助金额:$34.26万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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批准号:6899838
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项目类别:
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资助金额:$34.26万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
Structure Study of Angiopoietins and the Tie2 Receptor
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批准号:7101964
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项目类别:
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资助金额:$35.86万
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财政年份:2004
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负责人:DIMITAR B NIKOLOV
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依托单位:
海外基金