IDENTIFICATION OF C05C89 INTERACTING PROTEINS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 中心粒是一种小的圆柱形细胞器，它在微管的稳定中起重要作用，微管执行几种重要的细胞功能，包括中心体组装和纤毛形成。 了解中心粒如何执行这些不同的功能是非常有趣的。本项目的目标是鉴定C05C8.9相互作用蛋白。 C05C8.9是在SAS-4的TAP制备物中鉴定的一种新的中心粒蛋白，其是纤毛形成所需的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Centrioles are small cylindrical organelles that are important in the stabilization of microtubules which perform several important cellular functions including centrosome assembly and cilia formation. Understanding how centrioles perform these different functions is of great interest. The goal of this project is to identify C05C8.9 interacting proteins. C05C8.9 is a novel centriolar protein that was identified in a TAP preparation of SAS-4 which is required for cilia formation.