CLINICAL COMPUTATIONAL ANATOMY

临床计算解剖学

• 批准号: 8169701
• 负责人: Ion-Florin Talos
• 金额: $ 42.81万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169701
• 关键词: Anatomic structures; Anatomy; Atlases; Brain; Clinical; Computer Retrieval of Information on Scientific Projects Database; Computers; Controlled Vocabulary; Development; Funding; Grant; Human; Image; Institution; Knowledge; Label; Life; MRI Scans; Medical; Motor; Neuroanatomy; Ontology; Parkinson Disease; Research; Research Personnel; Resolution; Resources; Scanning; Source; System; United States National Institutes of Health; Work; base; computational anatomy; multimodality; nervous system disorder

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Clinical Computational Anatomy (CCA) core develops vehicles for expressing medical knowledge that can be interpreted by both humans and computers. These venues include volumetric, geometric, structural, and functional atlases of anatomy. The core is working to develop an integrated anatomic atlas of the brain. The fully developed form of this atlas will include (1) a volumetric brain atlas based on high resolution, multimodality MRI scans of a living, normal subject; (2) expert labeling of the anatomic structures imaged in these scans; (3) linkage of these labels to established, controlled vocabularies and ontologies of anatomy; (4) and development of a new functional ontology that describes the functional neuroanatomy of the human motor system, which is implicated in a group of neurologic disorders that includes Parkinson's disease.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 临床计算解剖学（CCA）核心开发了用于表达人类和计算机都可以解释的医学知识的工具。这些场所包括解剖学的体积、几何、结构和功能图谱。核心是 致力于开发大脑的综合解剖图谱。充分发展的形式 该图谱将包括（1）基于高分辨率、多模态 活体正常受试者的MRI扫描;（2）解剖结构的专家标记 在这些扫描中成像;（3）将这些标签与已建立的受控词汇表联系起来 和解剖学本体论;（4）和一个新的功能本体论的发展， 描述了人类运动系统的功能神经解剖学， 包括帕金森氏症在内的一组神经系统疾病。