CLINICAL COMPUTATIONAL ANATOMY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 临床计算解剖学(CCA)核心开发了表达人类和计算机都能解释的医学知识的工具。这些场馆包括体积、几何、结构和功能解剖学图集。核心是 致力于开发一份完整的大脑解剖图谱。完全开发的形式 该图谱将包括(1)基于高分辨率、多模式的体积脑图谱 活体正常受试者的核磁共振扫描；(2)解剖结构的专家标记 在这些扫描中成像；(3)这些标签与已建立的受控词汇表的链接 和解剖学的本体论；(4)和开发一种新的功能本体论， 描述了人体运动系统的功能神经解剖学，这与 在包括帕金森氏症在内的一组神经系统疾病中。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Clinical Computational Anatomy (CCA) core develops vehicles for expressing medical knowledge that can be interpreted by both humans and computers. These venues include volumetric, geometric, structural, and functional atlases of anatomy. The core is working to develop an integrated anatomic atlas of the brain. The fully developed form of this atlas will include (1) a volumetric brain atlas based on high resolution, multimodality MRI scans of a living, normal subject; (2) expert labeling of the anatomic structures imaged in these scans; (3) linkage of these labels to established, controlled vocabularies and ontologies of anatomy; (4) and development of a new functional ontology that describes the functional neuroanatomy of the human motor system, which is implicated in a group of neurologic disorders that includes Parkinson's disease.